GSM5528630

Dataset: gse182409 • Sample: T134 • Status: Pregnancy-stage cohort
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Quality Control Metrics

61,762,448 Total counts Group median: 70,855,220 • 24.3%ile (↓ Low)
32,770 Detected genes Group median: 31,576 • 79.1%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 42.8%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

47.2Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.66
bar=donor   line=cohort median 		9.31 77.6%
CETP Lipid Metabolism 1.15
bar=donor   line=cohort median 		1.18 45.2%
SIRT6 Sirtuin Family 1.96
bar=donor   line=cohort median 		2.22 21.7%
SIRT1 Sirtuin Family 5.58
bar=donor   line=cohort median 		5.50 65.2%
SIRT3 Sirtuin Family 2.23
bar=donor   line=cohort median 		2.33 32.1%
IGF1R Insulin/IGF-1 Signaling 7.26
bar=donor   line=cohort median 		7.09 72.8%
KLOTHO Anti-aging 1.47
bar=donor   line=cohort median 		0.66 95.5%
IRS2 Insulin/IGF-1 Signaling 5.31
bar=donor   line=cohort median 		5.59 27.2%
TP53 Tumor Suppression 2.04
bar=donor   line=cohort median 		2.72 10.7%
SHC1 Signal Transduction 3.80
bar=donor   line=cohort median 		3.95 23.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.9 1,985,545
2 ENSG00000258486 ENSG00000258486 14.9 1,926,932
3 7SK ENSG00000202198 misc_RNA 14.2 1,193,837
4 MALAT1 ENSG00000251562 lncRNA 13.6 791,223
5 B2M ENSG00000166710 protein_coding 13.1 543,340
6 S100A9 ENSG00000163220 protein_coding 12.7 419,978
7 AL355075.4 ENSG00000259001 lncRNA 12.7 416,210
8 EEF1A1 ENSG00000156508 protein_coding 12.4 338,904
9 ALAS2 ENSG00000158578 protein_coding 12.3 329,922
10 BNIP3L ENSG00000104765 protein_coding 12.3 310,264

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.5
bar=donor   line=cohort median 		11.8 11.8 30.5%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 19.5%
3 IL1B protein_coding 6.0
bar=donor   line=cohort median 		6.9 6.9 9.2%
4 CXCL8 protein_coding 7.5
bar=donor   line=cohort median 		7.6 7.6 48.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.2
bar=donor   line=cohort median 		4.0 4.0 54.5%
6 FCGR3B protein_coding 10.5
bar=donor   line=cohort median 		11.3 11.3 8.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.4
bar=donor   line=cohort median 		10.9 10.9 89.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.4
bar=donor   line=cohort median 		5.3 5.3 62.0%
9 CD3E protein_coding 2.5
bar=donor   line=cohort median 		2.6 2.6 44.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.5
bar=donor   line=cohort median 		6.3 6.3 4.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.0
bar=donor   line=cohort median 		3.4 3.4 29.1%
12 GNLY protein_coding 5.7
bar=donor   line=cohort median 		4.9 4.9 90.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.8
bar=donor   line=cohort median 		6.6 6.6 31.8%
14 HBA1 protein_coding 0.2
bar=donor   line=cohort median 		2.6 2.6 21.6%
15 HBA2 protein_coding 3.0
bar=donor   line=cohort median 		5.6 5.6 15.4%
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