GSM5528631

Dataset: gse182409 • Sample: T135 • Status: Pregnancy-stage cohort
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Quality Control Metrics

67,182,371 Total counts Group median: 70,855,220 • 40.1%ile (≈ Median)
29,826 Detected genes Group median: 31,576 • 34.6%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 59.2%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

39.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.81
bar=donor   line=cohort median 		9.31 14.1%
CETP Lipid Metabolism 1.17
bar=donor   line=cohort median 		1.18 49.3%
SIRT6 Sirtuin Family 1.76
bar=donor   line=cohort median 		2.22 4.5%
SIRT1 Sirtuin Family 5.52
bar=donor   line=cohort median 		5.50 57.6%
SIRT3 Sirtuin Family 2.39
bar=donor   line=cohort median 		2.33 59.0%
IGF1R Insulin/IGF-1 Signaling 6.88
bar=donor   line=cohort median 		7.09 30.0%
KLOTHO Anti-aging 0.02
bar=donor   line=cohort median 		0.66 14.1%
IRS2 Insulin/IGF-1 Signaling 5.69
bar=donor   line=cohort median 		5.59 60.3%
TP53 Tumor Suppression 2.78
bar=donor   line=cohort median 		2.72 55.5%
SHC1 Signal Transduction 3.92
bar=donor   line=cohort median 		3.95 46.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.3 1,301,103
2 ENSG00000258486 ENSG00000258486 14.2 1,223,961
3 ENSG00000265150 ENSG00000265150 14.2 1,194,734
4 B2M ENSG00000166710 protein_coding 13.5 748,185
5 AL355075.4 ENSG00000259001 lncRNA 13.2 583,101
6 MALAT1 ENSG00000251562 lncRNA 13.1 572,520
7 ALAS2 ENSG00000158578 protein_coding 13.0 532,768
8 S100A9 ENSG00000163220 protein_coding 12.9 497,953
9 BNIP3L ENSG00000104765 protein_coding 12.7 420,517
10 SLC25A37 ENSG00000147454 protein_coding 12.6 385,669

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.6
bar=donor   line=cohort median 		11.8 11.8 38.7%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median 		13.1 13.1 38.7%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 51.0%
4 CXCL8 protein_coding 8.2
bar=donor   line=cohort median 		7.6 7.6 72.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.2
bar=donor   line=cohort median 		4.0 4.0 82.5%
6 FCGR3B protein_coding 10.3
bar=donor   line=cohort median 		11.3 11.3 3.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.4
bar=donor   line=cohort median 		10.9 10.9 86.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 72.3%
9 CD3E protein_coding 1.7
bar=donor   line=cohort median 		2.6 2.6 9.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median 		6.3 6.3 55.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.1
bar=donor   line=cohort median 		3.4 3.4 31.2%
12 GNLY protein_coding 4.3
bar=donor   line=cohort median 		4.9 4.9 18.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.4
bar=donor   line=cohort median 		6.6 6.6 23.6%
14 HBA1 protein_coding 2.7
bar=donor   line=cohort median 		2.6 2.6 51.7%
15 HBA2 protein_coding 5.8
bar=donor   line=cohort median 		5.6 5.6 52.4%
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