GSM5528633

Dataset: gse182409 • Sample: T137 • Status: Pregnancy-stage cohort
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Quality Control Metrics

79,276,709 Total counts Group median: 70,855,220 • 69.5%ile (≈ Median)
33,625 Detected genes Group median: 31,576 • 93.5%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 65.4%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

37.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.12
bar=donor   line=cohort median 		9.31 34.8%
CETP Lipid Metabolism 1.36
bar=donor   line=cohort median 		1.18 63.8%
SIRT6 Sirtuin Family 2.40
bar=donor   line=cohort median 		2.22 77.6%
SIRT1 Sirtuin Family 5.38
bar=donor   line=cohort median 		5.50 21.7%
SIRT3 Sirtuin Family 2.47
bar=donor   line=cohort median 		2.33 70.7%
IGF1R Insulin/IGF-1 Signaling 6.24
bar=donor   line=cohort median 		7.09 2.4%
KLOTHO Anti-aging 0.43
bar=donor   line=cohort median 		0.66 29.3%
IRS2 Insulin/IGF-1 Signaling 5.15
bar=donor   line=cohort median 		5.59 18.3%
TP53 Tumor Suppression 2.71
bar=donor   line=cohort median 		2.72 47.9%
SHC1 Signal Transduction 3.56
bar=donor   line=cohort median 		3.95 4.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.3 3,394,358
2 ENSG00000258486 ENSG00000258486 15.1 3,019,826
3 7SK ENSG00000202198 misc_RNA 13.9 1,316,344
4 MALAT1 ENSG00000251562 lncRNA 13.6 1,061,531
5 AL355075.4 ENSG00000259001 lncRNA 13.0 674,529
6 B2M ENSG00000166710 protein_coding 12.9 651,361
7 BNIP3L ENSG00000104765 protein_coding 12.5 503,080
8 S100A9 ENSG00000163220 protein_coding 12.5 475,542
9 EEF1A1 ENSG00000156508 protein_coding 12.2 388,471
10 SOD2 ENSG00000112096 protein_coding 12.0 334,808

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.0
bar=donor   line=cohort median 		11.8 11.8 6.5%
2 S100A9 protein_coding 12.5
bar=donor   line=cohort median 		13.1 13.1 8.6%
3 IL1B protein_coding 6.3
bar=donor   line=cohort median 		6.9 6.9 20.2%
4 CXCL8 protein_coding 5.4
bar=donor   line=cohort median 		7.6 7.6 4.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.4
bar=donor   line=cohort median 		4.0 4.0 33.9%
6 FCGR3B protein_coding 10.6
bar=donor   line=cohort median 		11.3 11.3 9.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.1
bar=donor   line=cohort median 		10.9 10.9 7.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 49.0%
9 CD3E protein_coding 3.2
bar=donor   line=cohort median 		2.6 2.6 81.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median 		6.3 6.3 86.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.3
bar=donor   line=cohort median 		3.4 3.4 44.9%
12 GNLY protein_coding 4.7
bar=donor   line=cohort median 		4.9 4.9 35.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.1
bar=donor   line=cohort median 		6.6 6.6 14.7%
14 HBA1 protein_coding -0.3
bar=donor   line=cohort median 		2.6 2.6 17.5%
15 HBA2 protein_coding 3.3
bar=donor   line=cohort median 		5.6 5.6 22.9%
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