GSM5528643

Dataset: gse182409 • Sample: T147 • Status: Pregnancy-stage cohort
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Quality Control Metrics

74,102,431 Total counts Group median: 70,855,220 • 57.2%ile (≈ Median)
32,656 Detected genes Group median: 31,576 • 75.7%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 81.8%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

41.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.78
bar=donor   line=cohort median 		9.31 12.1%
CETP Lipid Metabolism 1.46
bar=donor   line=cohort median 		1.18 70.0%
SIRT6 Sirtuin Family 2.15
bar=donor   line=cohort median 		2.22 43.1%
SIRT1 Sirtuin Family 5.61
bar=donor   line=cohort median 		5.50 71.4%
SIRT3 Sirtuin Family 2.24
bar=donor   line=cohort median 		2.33 36.2%
IGF1R Insulin/IGF-1 Signaling 7.35
bar=donor   line=cohort median 		7.09 77.6%
KLOTHO Anti-aging -0.13
bar=donor   line=cohort median 		0.66 5.9%
IRS2 Insulin/IGF-1 Signaling 5.35
bar=donor   line=cohort median 		5.59 28.6%
TP53 Tumor Suppression 2.79
bar=donor   line=cohort median 		2.72 56.9%
SHC1 Signal Transduction 3.72
bar=donor   line=cohort median 		3.95 14.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.5 1,579,451
2 ENSG00000258486 ENSG00000258486 14.3 1,412,615
3 7SK ENSG00000202198 misc_RNA 14.0 1,142,350
4 MALAT1 ENSG00000251562 lncRNA 13.5 825,811
5 S100A9 ENSG00000163220 protein_coding 13.2 673,613
6 B2M ENSG00000166710 protein_coding 13.0 585,681
7 AL355075.4 ENSG00000259001 lncRNA 12.6 445,918
8 HBB ENSG00000244734 protein_coding 12.6 426,390
9 NAMPT ENSG00000105835 protein_coding 12.4 387,164
10 ALAS2 ENSG00000158578 protein_coding 12.3 351,684

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.7
bar=donor   line=cohort median 		11.8 11.8 44.2%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 65.4%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 54.5%
4 CXCL8 protein_coding 8.5
bar=donor   line=cohort median 		7.6 7.6 83.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.1
bar=donor   line=cohort median 		4.0 4.0 77.7%
6 FCGR3B protein_coding 11.4
bar=donor   line=cohort median 		11.3 11.3 56.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.4
bar=donor   line=cohort median 		10.9 10.9 15.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 42.1%
9 CD3E protein_coding 3.5
bar=donor   line=cohort median 		2.6 2.6 89.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.5
bar=donor   line=cohort median 		6.3 6.3 64.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.4
bar=donor   line=cohort median 		3.4 3.4 88.0%
12 GNLY protein_coding 5.3
bar=donor   line=cohort median 		4.9 4.9 75.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 12.6
bar=donor   line=cohort median 		6.6 6.6 95.5%
14 HBA1 protein_coding 6.9
bar=donor   line=cohort median 		2.6 2.6 90.1%
15 HBA2 protein_coding 11.4
bar=donor   line=cohort median 		5.6 5.6 97.6%
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