GSM5528644

Dataset: gse182409 • Sample: T148 • Status: Pregnancy-stage cohort
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Quality Control Metrics

82,869,690 Total counts Group median: 70,855,220 • 76.4%ile (↑ High)
31,489 Detected genes Group median: 31,576 • 49.0%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 86.0%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

67.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.81
bar=donor   line=cohort median 		9.31 14.8%
CETP Lipid Metabolism 1.40
bar=donor   line=cohort median 		1.18 67.9%
SIRT6 Sirtuin Family 2.38
bar=donor   line=cohort median 		2.22 74.1%
SIRT1 Sirtuin Family 5.60
bar=donor   line=cohort median 		5.50 69.3%
SIRT3 Sirtuin Family 2.50
bar=donor   line=cohort median 		2.33 74.1%
IGF1R Insulin/IGF-1 Signaling 7.13
bar=donor   line=cohort median 		7.09 54.1%
KLOTHO Anti-aging 0.69
bar=donor   line=cohort median 		0.66 52.8%
IRS2 Insulin/IGF-1 Signaling 6.12
bar=donor   line=cohort median 		5.59 89.3%
TP53 Tumor Suppression 3.74
bar=donor   line=cohort median 		2.72 95.5%
SHC1 Signal Transduction 4.24
bar=donor   line=cohort median 		3.95 87.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 13.8 1,184,046
2 ALAS2 ENSG00000158578 protein_coding 13.8 1,183,220
3 MALAT1 ENSG00000251562 lncRNA 13.7 1,094,130
4 ENSG00000265150 ENSG00000265150 13.6 1,032,976
5 ENSG00000258486 ENSG00000258486 13.3 867,039
6 B2M ENSG00000166710 protein_coding 13.0 667,573
7 S100A9 ENSG00000163220 protein_coding 12.7 564,993
8 NAMPT ENSG00000105835 protein_coding 12.5 501,036
9 AL355075.4 ENSG00000259001 lncRNA 12.5 488,949
10 SLC25A37 ENSG00000147454 protein_coding 12.3 430,903

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.6
bar=donor   line=cohort median 		11.8 11.8 33.2%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 20.9%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 53.8%
4 CXCL8 protein_coding 8.0
bar=donor   line=cohort median 		7.6 7.6 65.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.3
bar=donor   line=cohort median 		4.0 4.0 29.8%
6 FCGR3B protein_coding 11.1
bar=donor   line=cohort median 		11.3 11.3 36.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 77.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.9
bar=donor   line=cohort median 		5.3 5.3 12.0%
9 CD3E protein_coding 3.7
bar=donor   line=cohort median 		2.6 2.6 92.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.2
bar=donor   line=cohort median 		6.3 6.3 1.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 5.0
bar=donor   line=cohort median 		3.4 3.4 97.6%
12 GNLY protein_coding 5.6
bar=donor   line=cohort median 		4.9 4.9 86.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.9
bar=donor   line=cohort median 		6.6 6.6 66.8%
14 HBA1 protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 55.1%
15 HBA2 protein_coding 4.1
bar=donor   line=cohort median 		5.6 5.6 34.6%
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