GSM5528645

Dataset: gse182409 • Sample: T149 • Status: Pregnancy-stage cohort
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Quality Control Metrics

79,370,407 Total counts Group median: 70,855,220 • 70.2%ile (≈ Median)
34,663 Detected genes Group median: 31,576 • 99.0%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 82.5%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

73.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.56
bar=donor   line=cohort median 		9.31 69.3%
CETP Lipid Metabolism 1.54
bar=donor   line=cohort median 		1.18 72.8%
SIRT6 Sirtuin Family 2.38
bar=donor   line=cohort median 		2.22 71.4%
SIRT1 Sirtuin Family 5.37
bar=donor   line=cohort median 		5.50 20.3%
SIRT3 Sirtuin Family 2.99
bar=donor   line=cohort median 		2.33 97.6%
IGF1R Insulin/IGF-1 Signaling 7.51
bar=donor   line=cohort median 		7.09 90.0%
KLOTHO Anti-aging 0.27
bar=donor   line=cohort median 		0.66 21.7%
IRS2 Insulin/IGF-1 Signaling 6.57
bar=donor   line=cohort median 		5.59 97.6%
TP53 Tumor Suppression 3.73
bar=donor   line=cohort median 		2.72 94.8%
SHC1 Signal Transduction 4.34
bar=donor   line=cohort median 		3.95 95.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.0 2,702,694
2 ENSG00000265150 ENSG00000265150 15.0 2,662,055
3 7SK ENSG00000202198 misc_RNA 14.7 2,215,778
4 MALAT1 ENSG00000251562 lncRNA 13.6 996,694
5 AL355075.4 ENSG00000259001 lncRNA 13.5 964,273
6 B2M ENSG00000166710 protein_coding 13.2 752,446
7 S100A9 ENSG00000163220 protein_coding 12.8 568,392
8 ALAS2 ENSG00000158578 protein_coding 12.5 471,865
9 EEF1A1 ENSG00000156508 protein_coding 12.5 464,933
10 SLC25A37 ENSG00000147454 protein_coding 12.1 372,446

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.7
bar=donor   line=cohort median 		11.8 11.8 42.1%
2 S100A9 protein_coding 12.8
bar=donor   line=cohort median 		13.1 13.1 27.7%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 65.4%
4 CXCL8 protein_coding 6.6
bar=donor   line=cohort median 		7.6 7.6 18.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.2
bar=donor   line=cohort median 		4.0 4.0 57.2%
6 FCGR3B protein_coding 11.1
bar=donor   line=cohort median 		11.3 11.3 32.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.3
bar=donor   line=cohort median 		10.9 10.9 81.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.7
bar=donor   line=cohort median 		5.3 5.3 88.7%
9 CD3E protein_coding 3.2
bar=donor   line=cohort median 		2.6 2.6 77.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.7
bar=donor   line=cohort median 		6.3 6.3 79.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.5
bar=donor   line=cohort median 		3.4 3.4 53.1%
12 GNLY protein_coding 5.1
bar=donor   line=cohort median 		4.9 4.9 62.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.1
bar=donor   line=cohort median 		6.6 6.6 69.5%
14 HBA1 protein_coding 2.2
bar=donor   line=cohort median 		2.6 2.6 44.9%
15 HBA2 protein_coding 5.3
bar=donor   line=cohort median 		5.6 5.6 44.2%
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