GSM5528646

Dataset: gse182409 • Sample: T150 • Status: Pregnancy-stage cohort
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Quality Control Metrics

88,741,736 Total counts Group median: 70,855,220 • 88.0%ile (↑ High)
32,664 Detected genes Group median: 31,576 • 77.1%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 95.5%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

36.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.89
bar=donor   line=cohort median 		9.31 18.3%
CETP Lipid Metabolism 1.11
bar=donor   line=cohort median 		1.18 43.1%
SIRT6 Sirtuin Family 2.02
bar=donor   line=cohort median 		2.22 24.5%
SIRT1 Sirtuin Family 5.53
bar=donor   line=cohort median 		5.50 60.3%
SIRT3 Sirtuin Family 2.16
bar=donor   line=cohort median 		2.33 23.8%
IGF1R Insulin/IGF-1 Signaling 6.91
bar=donor   line=cohort median 		7.09 34.8%
KLOTHO Anti-aging -0.05
bar=donor   line=cohort median 		0.66 11.4%
IRS2 Insulin/IGF-1 Signaling 5.43
bar=donor   line=cohort median 		5.59 34.8%
TP53 Tumor Suppression 2.88
bar=donor   line=cohort median 		2.72 60.3%
SHC1 Signal Transduction 3.94
bar=donor   line=cohort median 		3.95 48.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.8 2,309,696
2 ENSG00000258486 ENSG00000258486 14.5 1,898,815
3 7SK ENSG00000202198 misc_RNA 13.8 1,183,137
4 MALAT1 ENSG00000251562 lncRNA 13.5 931,714
5 ALAS2 ENSG00000158578 protein_coding 13.3 813,508
6 B2M ENSG00000166710 protein_coding 13.0 656,017
7 S100A9 ENSG00000163220 protein_coding 12.8 591,130
8 AL355075.4 ENSG00000259001 lncRNA 12.6 499,059
9 SLC25A37 ENSG00000147454 protein_coding 12.3 409,941
10 NAMPT ENSG00000105835 protein_coding 12.3 409,500

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.2
bar=donor   line=cohort median 		11.8 11.8 12.0%
2 S100A9 protein_coding 12.8
bar=donor   line=cohort median 		13.1 13.1 29.8%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 57.9%
4 CXCL8 protein_coding 6.5
bar=donor   line=cohort median 		7.6 7.6 17.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.4
bar=donor   line=cohort median 		4.0 4.0 32.5%
6 FCGR3B protein_coding 11.5
bar=donor   line=cohort median 		11.3 11.3 62.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.4
bar=donor   line=cohort median 		10.9 10.9 85.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.3
bar=donor   line=cohort median 		5.3 5.3 0.3%
9 CD3E protein_coding 3.3
bar=donor   line=cohort median 		2.6 2.6 84.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.8
bar=donor   line=cohort median 		6.3 6.3 16.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.4
bar=donor   line=cohort median 		3.4 3.4 86.0%
12 GNLY protein_coding 5.0
bar=donor   line=cohort median 		4.9 4.9 59.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.9
bar=donor   line=cohort median 		6.6 6.6 33.9%
14 HBA1 protein_coding 2.5
bar=donor   line=cohort median 		2.6 2.6 48.3%
15 HBA2 protein_coding 5.6
bar=donor   line=cohort median 		5.6 5.6 50.3%
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