GSM5528648

Dataset: gse182409 • Sample: T152 • Status: Pregnancy-stage cohort
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Quality Control Metrics

103,002,082 Total counts Group median: 70,855,220 • 96.9%ile (↑ High)
31,711 Detected genes Group median: 31,576 • 53.1%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 74.3%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

41.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.72
bar=donor   line=cohort median 		9.31 10.7%
CETP Lipid Metabolism 0.88
bar=donor   line=cohort median 		1.18 29.3%
SIRT6 Sirtuin Family 1.76
bar=donor   line=cohort median 		2.22 3.8%
SIRT1 Sirtuin Family 5.45
bar=donor   line=cohort median 		5.50 35.5%
SIRT3 Sirtuin Family 2.54
bar=donor   line=cohort median 		2.33 80.3%
IGF1R Insulin/IGF-1 Signaling 6.97
bar=donor   line=cohort median 		7.09 39.0%
KLOTHO Anti-aging 0.73
bar=donor   line=cohort median 		0.66 56.9%
IRS2 Insulin/IGF-1 Signaling 5.91
bar=donor   line=cohort median 		5.59 81.0%
TP53 Tumor Suppression 2.74
bar=donor   line=cohort median 		2.72 52.1%
SHC1 Signal Transduction 3.79
bar=donor   line=cohort median 		3.95 22.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.3 1,524,913
2 ENSG00000265150 ENSG00000265150 13.4 847,780
3 ENSG00000258486 ENSG00000258486 13.3 800,360
4 B2M ENSG00000166710 protein_coding 13.2 713,901
5 MALAT1 ENSG00000251562 lncRNA 13.1 676,902
6 S100A9 ENSG00000163220 protein_coding 13.1 674,150
7 AL355075.4 ENSG00000259001 lncRNA 12.8 559,340
8 NAMPT ENSG00000105835 protein_coding 12.4 430,099
9 SORL1 ENSG00000137642 protein_coding 12.2 367,838
10 EEF1A1 ENSG00000156508 protein_coding 12.2 365,285

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.8
bar=donor   line=cohort median 		11.8 11.8 51.0%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 46.9%
3 IL1B protein_coding 7.2
bar=donor   line=cohort median 		6.9 6.9 75.0%
4 CXCL8 protein_coding 8.8
bar=donor   line=cohort median 		7.6 7.6 89.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.0
bar=donor   line=cohort median 		4.0 4.0 75.7%
6 FCGR3B protein_coding 11.1
bar=donor   line=cohort median 		11.3 11.3 34.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 57.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 70.2%
9 CD3E protein_coding 3.0
bar=donor   line=cohort median 		2.6 2.6 70.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.0
bar=donor   line=cohort median 		6.3 6.3 31.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.4
bar=donor   line=cohort median 		3.4 3.4 86.6%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median 		4.9 4.9 54.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.4
bar=donor   line=cohort median 		6.6 6.6 83.9%
14 HBA1 protein_coding 7.4
bar=donor   line=cohort median 		2.6 2.6 95.5%
15 HBA2 protein_coding 10.5
bar=donor   line=cohort median 		5.6 5.6 92.1%
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