GSM5528652

Dataset: gse182409 • Sample: T156 • Status: Pregnancy-stage cohort

Quality Control Metrics

69,433,670 Total counts Group median: 70,855,220 • 46.2%ile (≈ Median)
29,937 Detected genes Group median: 31,576 • 36.6%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 84.6%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

38.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.58
bar=donor   line=cohort median
9.31 71.4%
CETP Lipid Metabolism 0.63
bar=donor   line=cohort median
1.18 14.1%
SIRT6 Sirtuin Family 2.09
bar=donor   line=cohort median
2.22 34.1%
SIRT1 Sirtuin Family 5.63
bar=donor   line=cohort median
5.50 73.5%
SIRT3 Sirtuin Family 2.32
bar=donor   line=cohort median
2.33 49.3%
IGF1R Insulin/IGF-1 Signaling 6.69
bar=donor   line=cohort median
7.09 14.8%
KLOTHO Anti-aging -0.17
bar=donor   line=cohort median
0.66 4.5%
IRS2 Insulin/IGF-1 Signaling 6.10
bar=donor   line=cohort median
5.59 88.6%
TP53 Tumor Suppression 2.21
bar=donor   line=cohort median
2.72 21.0%
SHC1 Signal Transduction 3.65
bar=donor   line=cohort median
3.95 11.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.4 1,427,650
2 ENSG00000265150 ENSG00000265150 13.3 663,382
3 ENSG00000258486 ENSG00000258486 13.3 662,582
4 B2M ENSG00000166710 protein_coding 13.2 623,099
5 S100A9 ENSG00000163220 protein_coding 13.2 614,007
6 MALAT1 ENSG00000251562 lncRNA 13.0 536,753
7 AL355075.4 ENSG00000259001 lncRNA 13.0 531,454
8 ALAS2 ENSG00000158578 protein_coding 12.9 486,028
9 SLC25A37 ENSG00000147454 protein_coding 12.5 362,091
10 BNIP3L ENSG00000104765 protein_coding 12.4 354,753

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median
11.8 11.8 70.2%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median
13.1 13.1 61.3%
3 IL1B protein_coding 7.1
bar=donor   line=cohort median
6.9 6.9 70.2%
4 CXCL8 protein_coding 7.4
bar=donor   line=cohort median
7.6 7.6 45.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 6.7
bar=donor   line=cohort median
4.0 4.0 99.0%
6 FCGR3B protein_coding 11.1
bar=donor   line=cohort median
11.3 11.3 30.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.1
bar=donor   line=cohort median
10.9 10.9 64.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.8
bar=donor   line=cohort median
5.3 5.3 7.2%
9 CD3E protein_coding 1.9
bar=donor   line=cohort median
2.6 2.6 14.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median
6.3 6.3 50.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median
3.4 3.4 70.9%
12 GNLY protein_coding 5.0
bar=donor   line=cohort median
4.9 4.9 57.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.2
bar=donor   line=cohort median
6.6 6.6 41.4%
14 HBA1 protein_coding 4.9
bar=donor   line=cohort median
2.6 2.6 75.0%
15 HBA2 protein_coding 7.8
bar=donor   line=cohort median
5.6 5.6 72.3%