GSM5528654

Dataset: gse182409 • Sample: T158 • Status: Pregnancy-stage cohort
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Quality Control Metrics

70,736,928 Total counts Group median: 70,855,220 • 49.0%ile (≈ Median)
33,177 Detected genes Group median: 31,576 • 85.3%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 49.7%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

50.4Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.08
bar=donor   line=cohort median 		9.31 32.1%
CETP Lipid Metabolism 0.66
bar=donor   line=cohort median 		1.18 15.5%
SIRT6 Sirtuin Family 2.64
bar=donor   line=cohort median 		2.22 93.5%
SIRT1 Sirtuin Family 5.08
bar=donor   line=cohort median 		5.50 1.0%
SIRT3 Sirtuin Family 2.47
bar=donor   line=cohort median 		2.33 71.4%
IGF1R Insulin/IGF-1 Signaling 6.98
bar=donor   line=cohort median 		7.09 39.7%
KLOTHO Anti-aging 0.34
bar=donor   line=cohort median 		0.66 23.8%
IRS2 Insulin/IGF-1 Signaling 6.35
bar=donor   line=cohort median 		5.59 96.2%
TP53 Tumor Suppression 2.82
bar=donor   line=cohort median 		2.72 59.0%
SHC1 Signal Transduction 4.10
bar=donor   line=cohort median 		3.95 72.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.8 1,811,663
2 ENSG00000258486 ENSG00000258486 14.7 1,701,098
3 7SK ENSG00000202198 misc_RNA 14.5 1,481,589
4 MALAT1 ENSG00000251562 lncRNA 13.8 884,759
5 AL355075.4 ENSG00000259001 lncRNA 13.5 754,507
6 B2M ENSG00000166710 protein_coding 13.4 698,593
7 S100A9 ENSG00000163220 protein_coding 13.4 677,419
8 ALAS2 ENSG00000158578 protein_coding 13.3 629,800
9 NAMPT ENSG00000105835 protein_coding 13.0 540,569
10 SLC25A37 ENSG00000147454 protein_coding 12.4 333,810

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median 		11.8 11.8 71.6%
2 S100A9 protein_coding 13.4
bar=donor   line=cohort median 		13.1 13.1 79.1%
3 IL1B protein_coding 7.5
bar=donor   line=cohort median 		6.9 6.9 90.1%
4 CXCL8 protein_coding 8.4
bar=donor   line=cohort median 		7.6 7.6 79.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.5
bar=donor   line=cohort median 		4.0 4.0 9.9%
6 FCGR3B protein_coding 11.4
bar=donor   line=cohort median 		11.3 11.3 59.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.9
bar=donor   line=cohort median 		10.9 10.9 48.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.0
bar=donor   line=cohort median 		5.3 5.3 20.2%
9 CD3E protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 74.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.0
bar=donor   line=cohort median 		6.3 6.3 33.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.2
bar=donor   line=cohort median 		3.4 3.4 36.0%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 45.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.7
bar=donor   line=cohort median 		6.6 6.6 28.4%
14 HBA1 protein_coding 1.7
bar=donor   line=cohort median 		2.6 2.6 38.0%
15 HBA2 protein_coding 3.7
bar=donor   line=cohort median 		5.6 5.6 28.4%
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