GSM5528655

Dataset: gse182409 • Sample: T159 • Status: Pregnancy-stage cohort
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Quality Control Metrics

78,831,222 Total counts Group median: 70,855,220 • 68.2%ile (≈ Median)
33,536 Detected genes Group median: 31,576 • 91.4%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 73.6%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

59.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.18
bar=donor   line=cohort median 		9.31 41.0%
CETP Lipid Metabolism 1.30
bar=donor   line=cohort median 		1.18 57.6%
SIRT6 Sirtuin Family 2.13
bar=donor   line=cohort median 		2.22 40.3%
SIRT1 Sirtuin Family 5.67
bar=donor   line=cohort median 		5.50 82.4%
SIRT3 Sirtuin Family 2.09
bar=donor   line=cohort median 		2.33 18.3%
IGF1R Insulin/IGF-1 Signaling 7.42
bar=donor   line=cohort median 		7.09 84.5%
KLOTHO Anti-aging 1.24
bar=donor   line=cohort median 		0.66 85.2%
IRS2 Insulin/IGF-1 Signaling 5.87
bar=donor   line=cohort median 		5.59 75.5%
TP53 Tumor Suppression 2.96
bar=donor   line=cohort median 		2.72 66.6%
SHC1 Signal Transduction 3.86
bar=donor   line=cohort median 		3.95 38.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.1 2,576,450
2 ENSG00000258486 ENSG00000258486 15.0 2,315,523
3 7SK ENSG00000202198 misc_RNA 14.6 1,789,684
4 MALAT1 ENSG00000251562 lncRNA 13.8 1,039,873
5 B2M ENSG00000166710 protein_coding 13.4 782,221
6 AL355075.4 ENSG00000259001 lncRNA 13.4 765,899
7 S100A9 ENSG00000163220 protein_coding 13.1 608,867
8 IFIT2 ENSG00000119922 protein_coding 12.8 496,717
9 NAMPT ENSG00000105835 protein_coding 12.7 491,232
10 ALAS2 ENSG00000158578 protein_coding 12.7 461,758

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.6
bar=donor   line=cohort median 		11.8 11.8 31.8%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 44.9%
3 IL1B protein_coding 7.5
bar=donor   line=cohort median 		6.9 6.9 92.1%
4 CXCL8 protein_coding 5.5
bar=donor   line=cohort median 		7.6 7.6 7.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.2
bar=donor   line=cohort median 		4.0 4.0 27.1%
6 FCGR3B protein_coding 11.5
bar=donor   line=cohort median 		11.3 11.3 60.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.1
bar=donor   line=cohort median 		10.9 10.9 66.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.4
bar=donor   line=cohort median 		5.3 5.3 61.3%
9 CD3E protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 75.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.4
bar=donor   line=cohort median 		6.3 6.3 60.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median 		3.4 3.4 67.5%
12 GNLY protein_coding 5.1
bar=donor   line=cohort median 		4.9 4.9 61.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.3
bar=donor   line=cohort median 		6.6 6.6 18.2%
14 HBA1 protein_coding 0.1
bar=donor   line=cohort median 		2.6 2.6 20.9%
15 HBA2 protein_coding 2.8
bar=donor   line=cohort median 		5.6 5.6 12.7%
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