GSM5528656

Dataset: gse182409 • Sample: T160 • Status: Pregnancy-stage cohort
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Quality Control Metrics

80,955,885 Total counts Group median: 70,855,220 • 72.3%ile (≈ Median)
31,719 Detected genes Group median: 31,576 • 53.8%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 13.4%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

45.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.95
bar=donor   line=cohort median 		9.31 21.7%
CETP Lipid Metabolism 1.81
bar=donor   line=cohort median 		1.18 85.2%
SIRT6 Sirtuin Family 2.01
bar=donor   line=cohort median 		2.22 23.8%
SIRT1 Sirtuin Family 5.48
bar=donor   line=cohort median 		5.50 39.7%
SIRT3 Sirtuin Family 2.06
bar=donor   line=cohort median 		2.33 13.5%
IGF1R Insulin/IGF-1 Signaling 7.20
bar=donor   line=cohort median 		7.09 62.4%
KLOTHO Anti-aging 0.75
bar=donor   line=cohort median 		0.66 57.6%
IRS2 Insulin/IGF-1 Signaling 5.57
bar=donor   line=cohort median 		5.59 45.2%
TP53 Tumor Suppression 3.07
bar=donor   line=cohort median 		2.72 72.8%
SHC1 Signal Transduction 3.86
bar=donor   line=cohort median 		3.95 37.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.1 2,661,744
2 ENSG00000258486 ENSG00000258486 15.0 2,396,244
3 7SK ENSG00000202198 misc_RNA 14.5 1,713,680
4 B2M ENSG00000166710 protein_coding 13.6 928,815
5 AL355075.4 ENSG00000259001 lncRNA 13.5 826,137
6 S100A9 ENSG00000163220 protein_coding 13.3 752,568
7 ALAS2 ENSG00000158578 protein_coding 13.2 712,178
8 MALAT1 ENSG00000251562 lncRNA 13.2 694,777
9 BNIP3L ENSG00000104765 protein_coding 13.1 637,724
10 NAMPT ENSG00000105835 protein_coding 12.9 561,629

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 55.8%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 74.3%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 64.7%
4 CXCL8 protein_coding 9.5
bar=donor   line=cohort median 		7.6 7.6 96.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.3
bar=donor   line=cohort median 		4.0 4.0 6.5%
6 FCGR3B protein_coding 11.9
bar=donor   line=cohort median 		11.3 11.3 88.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 60.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.9
bar=donor   line=cohort median 		5.3 5.3 94.2%
9 CD3E protein_coding 2.4
bar=donor   line=cohort median 		2.6 2.6 39.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.4
bar=donor   line=cohort median 		6.3 6.3 98.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 1.9
bar=donor   line=cohort median 		3.4 3.4 1.0%
12 GNLY protein_coding 3.4
bar=donor   line=cohort median 		4.9 4.9 1.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.1
bar=donor   line=cohort median 		6.6 6.6 15.4%
14 HBA1 protein_coding -0.5
bar=donor   line=cohort median 		2.6 2.6 12.0%
15 HBA2 protein_coding 3.0
bar=donor   line=cohort median 		5.6 5.6 14.7%
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