GSM5528658

Dataset: gse182409 • Sample: T162 • Status: Pregnancy-stage cohort
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Quality Control Metrics

53,670,367 Total counts Group median: 70,855,220 • 13.4%ile (↓ Low)
30,620 Detected genes Group median: 31,576 • 40.1%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 92.1%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

30.8Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.98
bar=donor   line=cohort median 		9.31 23.1%
CETP Lipid Metabolism 0.31
bar=donor   line=cohort median 		1.18 5.9%
SIRT6 Sirtuin Family 1.96
bar=donor   line=cohort median 		2.22 21.0%
SIRT1 Sirtuin Family 5.82
bar=donor   line=cohort median 		5.50 94.1%
SIRT3 Sirtuin Family 2.70
bar=donor   line=cohort median 		2.33 90.0%
IGF1R Insulin/IGF-1 Signaling 6.47
bar=donor   line=cohort median 		7.09 6.6%
KLOTHO Anti-aging -0.02
bar=donor   line=cohort median 		0.66 13.5%
IRS2 Insulin/IGF-1 Signaling 5.29
bar=donor   line=cohort median 		5.59 25.2%
TP53 Tumor Suppression 2.32
bar=donor   line=cohort median 		2.72 28.6%
SHC1 Signal Transduction 3.42
bar=donor   line=cohort median 		3.95 0.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.0 863,091
2 ENSG00000258486 ENSG00000258486 13.6 640,397
3 MALAT1 ENSG00000251562 lncRNA 13.5 608,570
4 B2M ENSG00000166710 protein_coding 13.1 439,966
5 ENSG00000265150 ENSG00000265150 12.7 340,623
6 ALAS2 ENSG00000158578 protein_coding 12.7 335,865
7 AL355075.4 ENSG00000259001 lncRNA 12.6 309,898
8 S100A9 ENSG00000163220 protein_coding 12.5 302,634
9 NAMPT ENSG00000105835 protein_coding 12.3 257,784
10 EEF1A1 ENSG00000156508 protein_coding 12.2 235,645

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.3
bar=donor   line=cohort median 		11.8 11.8 16.8%
2 S100A9 protein_coding 12.5
bar=donor   line=cohort median 		13.1 13.1 12.0%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 63.4%
4 CXCL8 protein_coding 8.8
bar=donor   line=cohort median 		7.6 7.6 88.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.3
bar=donor   line=cohort median 		4.0 4.0 83.9%
6 FCGR3B protein_coding 10.8
bar=donor   line=cohort median 		11.3 11.3 15.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 44.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.6
bar=donor   line=cohort median 		5.3 5.3 77.1%
9 CD3E protein_coding 2.8
bar=donor   line=cohort median 		2.6 2.6 59.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median 		6.3 6.3 53.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.0
bar=donor   line=cohort median 		3.4 3.4 77.7%
12 GNLY protein_coding 5.3
bar=donor   line=cohort median 		4.9 4.9 74.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 10.2
bar=donor   line=cohort median 		6.6 6.6 88.7%
14 HBA1 protein_coding 6.8
bar=donor   line=cohort median 		2.6 2.6 89.4%
15 HBA2 protein_coding 9.5
bar=donor   line=cohort median 		5.6 5.6 88.0%
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