GSM5528659

Dataset: gse182409 • Sample: T163 • Status: Pregnancy-stage cohort

Quality Control Metrics

108,640,948 Total counts Group median: 70,855,220 • 98.3%ile (↑ High)
28,669 Detected genes Group median: 31,576 • 22.9%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 44.2%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

42.8Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.71
bar=donor   line=cohort median
9.31 10.0%
CETP Lipid Metabolism 1.16
bar=donor   line=cohort median
1.18 47.9%
SIRT6 Sirtuin Family 1.82
bar=donor   line=cohort median
2.22 8.6%
SIRT1 Sirtuin Family 5.56
bar=donor   line=cohort median
5.50 62.4%
SIRT3 Sirtuin Family 2.26
bar=donor   line=cohort median
2.33 43.1%
IGF1R Insulin/IGF-1 Signaling 6.96
bar=donor   line=cohort median
7.09 38.3%
KLOTHO Anti-aging -0.03
bar=donor   line=cohort median
0.66 12.8%
IRS2 Insulin/IGF-1 Signaling 5.80
bar=donor   line=cohort median
5.59 67.9%
TP53 Tumor Suppression 2.72
bar=donor   line=cohort median
2.72 48.6%
SHC1 Signal Transduction 4.25
bar=donor   line=cohort median
3.95 88.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.0 2,804,709
2 ENSG00000258486 ENSG00000258486 14.8 2,487,117
3 7SK ENSG00000202198 misc_RNA 14.5 2,030,576
4 S100A9 ENSG00000163220 protein_coding 13.7 1,140,729
5 B2M ENSG00000166710 protein_coding 13.6 1,113,483
6 AL355075.4 ENSG00000259001 lncRNA 13.1 786,699
7 ALAS2 ENSG00000158578 protein_coding 13.1 773,329
8 NAMPT ENSG00000105835 protein_coding 12.9 668,238
9 MALAT1 ENSG00000251562 lncRNA 12.8 644,585
10 EEF1A1 ENSG00000156508 protein_coding 12.6 554,650

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.5
bar=donor   line=cohort median
11.8 11.8 93.5%
2 S100A9 protein_coding 13.7
bar=donor   line=cohort median
13.1 13.1 91.4%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median
6.9 6.9 49.7%
4 CXCL8 protein_coding 7.7
bar=donor   line=cohort median
7.6 7.6 53.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.6
bar=donor   line=cohort median
4.0 4.0 90.8%
6 FCGR3B protein_coding 11.7
bar=donor   line=cohort median
11.3 11.3 77.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 12.0
bar=donor   line=cohort median
10.9 10.9 99.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median
5.3 5.3 36.6%
9 CD3E protein_coding 2.1
bar=donor   line=cohort median
2.6 2.6 20.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.5
bar=donor   line=cohort median
6.3 6.3 3.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.6
bar=donor   line=cohort median
3.4 3.4 15.4%
12 GNLY protein_coding 3.8
bar=donor   line=cohort median
4.9 4.9 5.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.9
bar=donor   line=cohort median
6.6 6.6 67.5%
14 HBA1 protein_coding 6.1
bar=donor   line=cohort median
2.6 2.6 85.3%
15 HBA2 protein_coding 9.0
bar=donor   line=cohort median
5.6 5.6 84.6%