GSM5528660

Dataset: gse182409 • Sample: T164 • Status: Pregnancy-stage cohort
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Quality Control Metrics

68,955,402 Total counts Group median: 70,855,220 • 44.2%ile (≈ Median)
30,469 Detected genes Group median: 31,576 • 38.0%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 22.9%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

35.8Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.99
bar=donor   line=cohort median 		9.31 24.5%
CETP Lipid Metabolism 0.30
bar=donor   line=cohort median 		1.18 5.2%
SIRT6 Sirtuin Family 2.24
bar=donor   line=cohort median 		2.22 52.8%
SIRT1 Sirtuin Family 5.43
bar=donor   line=cohort median 		5.50 32.1%
SIRT3 Sirtuin Family 2.21
bar=donor   line=cohort median 		2.33 27.9%
IGF1R Insulin/IGF-1 Signaling 6.84
bar=donor   line=cohort median 		7.09 25.9%
KLOTHO Anti-aging -0.57
bar=donor   line=cohort median 		0.66 2.4%
IRS2 Insulin/IGF-1 Signaling 5.90
bar=donor   line=cohort median 		5.59 79.7%
TP53 Tumor Suppression 2.74
bar=donor   line=cohort median 		2.72 52.8%
SHC1 Signal Transduction 3.98
bar=donor   line=cohort median 		3.95 54.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 15.1 2,089,949
2 ENSG00000258486 ENSG00000258486 14.3 1,183,343
3 S100A9 ENSG00000163220 protein_coding 14.3 1,164,260
4 ENSG00000265150 ENSG00000265150 14.2 1,108,583
5 B2M ENSG00000166710 protein_coding 14.1 1,035,737
6 AL355075.4 ENSG00000259001 lncRNA 13.6 733,928
7 NAMPT ENSG00000105835 protein_coding 13.5 660,642
8 MALAT1 ENSG00000251562 lncRNA 13.4 626,778
9 S100A8 ENSG00000143546 protein_coding 13.0 464,205
10 SOD2 ENSG00000112096 protein_coding 12.9 442,858

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 13.0
bar=donor   line=cohort median 		11.8 11.8 99.7%
2 S100A9 protein_coding 14.3
bar=donor   line=cohort median 		13.1 13.1 99.7%
3 IL1B protein_coding 7.1
bar=donor   line=cohort median 		6.9 6.9 67.5%
4 CXCL8 protein_coding 9.5
bar=donor   line=cohort median 		7.6 7.6 97.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.0
bar=donor   line=cohort median 		4.0 4.0 5.8%
6 FCGR3B protein_coding 11.2
bar=donor   line=cohort median 		11.3 11.3 38.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 55.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 33.2%
9 CD3E protein_coding 2.3
bar=donor   line=cohort median 		2.6 2.6 36.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.6
bar=donor   line=cohort median 		6.3 6.3 70.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.4
bar=donor   line=cohort median 		3.4 3.4 50.3%
12 GNLY protein_coding 5.6
bar=donor   line=cohort median 		4.9 4.9 87.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.5
bar=donor   line=cohort median 		6.6 6.6 5.8%
14 HBA1 protein_coding -0.8
bar=donor   line=cohort median 		2.6 2.6 5.1%
15 HBA2 protein_coding 1.7
bar=donor   line=cohort median 		5.6 5.6 0.3%
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