GSM5528661

Dataset: gse182409 • Sample: T165 • Status: Pregnancy-stage cohort
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Quality Control Metrics

48,745,061 Total counts Group median: 70,855,220 • 5.8%ile (↓ Low)
30,963 Detected genes Group median: 31,576 • 42.8%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 36.6%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

45.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.18
bar=donor   line=cohort median 		9.31 41.7%
CETP Lipid Metabolism 1.32
bar=donor   line=cohort median 		1.18 61.0%
SIRT6 Sirtuin Family 2.04
bar=donor   line=cohort median 		2.22 26.6%
SIRT1 Sirtuin Family 5.48
bar=donor   line=cohort median 		5.50 41.7%
SIRT3 Sirtuin Family 2.25
bar=donor   line=cohort median 		2.33 39.7%
IGF1R Insulin/IGF-1 Signaling 7.17
bar=donor   line=cohort median 		7.09 57.6%
KLOTHO Anti-aging 0.67
bar=donor   line=cohort median 		0.66 50.7%
IRS2 Insulin/IGF-1 Signaling 5.86
bar=donor   line=cohort median 		5.59 73.5%
TP53 Tumor Suppression 2.06
bar=donor   line=cohort median 		2.72 12.1%
SHC1 Signal Transduction 3.95
bar=donor   line=cohort median 		3.95 50.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.5 1,970,749
2 ENSG00000258486 ENSG00000258486 15.3 1,710,624
3 7SK ENSG00000202198 misc_RNA 14.4 944,855
4 MALAT1 ENSG00000251562 lncRNA 13.8 609,256
5 ALAS2 ENSG00000158578 protein_coding 13.5 485,963
6 AL355075.4 ENSG00000259001 lncRNA 13.4 463,845
7 BNIP3L ENSG00000104765 protein_coding 13.2 406,451
8 S100A9 ENSG00000163220 protein_coding 13.1 373,005
9 B2M ENSG00000166710 protein_coding 13.1 366,438
10 EPB41 ENSG00000159023 protein_coding 12.8 314,326

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 62.0%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 46.2%
3 IL1B protein_coding 6.5
bar=donor   line=cohort median 		6.9 6.9 29.1%
4 CXCL8 protein_coding 7.8
bar=donor   line=cohort median 		7.6 7.6 61.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.2
bar=donor   line=cohort median 		4.0 4.0 27.7%
6 FCGR3B protein_coding 11.0
bar=donor   line=cohort median 		11.3 11.3 25.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.9
bar=donor   line=cohort median 		10.9 10.9 46.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.8
bar=donor   line=cohort median 		5.3 5.3 9.2%
9 CD3E protein_coding 2.5
bar=donor   line=cohort median 		2.6 2.6 46.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.1
bar=donor   line=cohort median 		6.3 6.3 38.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.2
bar=donor   line=cohort median 		3.4 3.4 37.3%
12 GNLY protein_coding 5.3
bar=donor   line=cohort median 		4.9 4.9 76.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.9
bar=donor   line=cohort median 		6.6 6.6 36.6%
14 HBA1 protein_coding 0.6
bar=donor   line=cohort median 		2.6 2.6 28.4%
15 HBA2 protein_coding 3.1
bar=donor   line=cohort median 		5.6 5.6 19.5%
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