GSM5528666

Dataset: gse182409 • Sample: T170 • Status: Pregnancy-stage cohort
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Quality Control Metrics

55,241,405 Total counts Group median: 70,855,220 • 14.7%ile (↓ Low)
30,608 Detected genes Group median: 31,576 • 39.4%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 79.8%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

67.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.98
bar=donor   line=cohort median 		9.31 87.9%
CETP Lipid Metabolism 2.25
bar=donor   line=cohort median 		1.18 94.8%
SIRT6 Sirtuin Family 2.36
bar=donor   line=cohort median 		2.22 69.3%
SIRT1 Sirtuin Family 5.34
bar=donor   line=cohort median 		5.50 12.8%
SIRT3 Sirtuin Family 2.33
bar=donor   line=cohort median 		2.33 54.1%
IGF1R Insulin/IGF-1 Signaling 7.36
bar=donor   line=cohort median 		7.09 78.3%
KLOTHO Anti-aging 0.32
bar=donor   line=cohort median 		0.66 23.1%
IRS2 Insulin/IGF-1 Signaling 5.78
bar=donor   line=cohort median 		5.59 66.6%
TP53 Tumor Suppression 3.62
bar=donor   line=cohort median 		2.72 93.5%
SHC1 Signal Transduction 4.39
bar=donor   line=cohort median 		3.95 96.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.8 1,338,043
2 ENSG00000258486 ENSG00000258486 14.6 1,192,660
3 7SK ENSG00000202198 misc_RNA 14.1 856,907
4 MALAT1 ENSG00000251562 lncRNA 13.3 490,201
5 S100A9 ENSG00000163220 protein_coding 13.2 461,348
6 B2M ENSG00000166710 protein_coding 13.2 451,876
7 ALAS2 ENSG00000158578 protein_coding 12.9 370,471
8 NAMPT ENSG00000105835 protein_coding 12.6 305,241
9 SORL1 ENSG00000137642 protein_coding 12.5 282,966
10 SLC25A37 ENSG00000147454 protein_coding 12.5 277,194

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.8
bar=donor   line=cohort median 		11.8 11.8 49.7%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 62.0%
3 IL1B protein_coding 7.5
bar=donor   line=cohort median 		6.9 6.9 89.4%
4 CXCL8 protein_coding 7.2
bar=donor   line=cohort median 		7.6 7.6 40.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.6
bar=donor   line=cohort median 		4.0 4.0 37.3%
6 FCGR3B protein_coding 11.4
bar=donor   line=cohort median 		11.3 11.3 57.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.9
bar=donor   line=cohort median 		10.9 10.9 49.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 28.4%
9 CD3E protein_coding 3.2
bar=donor   line=cohort median 		2.6 2.6 79.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.9
bar=donor   line=cohort median 		6.3 6.3 26.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.0
bar=donor   line=cohort median 		3.4 3.4 76.4%
12 GNLY protein_coding 5.4
bar=donor   line=cohort median 		4.9 4.9 83.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.1
bar=donor   line=cohort median 		6.6 6.6 68.8%
14 HBA1 protein_coding 5.9
bar=donor   line=cohort median 		2.6 2.6 83.2%
15 HBA2 protein_coding 8.9
bar=donor   line=cohort median 		5.6 5.6 83.9%
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