GSM5528668

Dataset: gse182409 • Sample: T172 • Status: Pregnancy-stage cohort
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Quality Control Metrics

77,518,315 Total counts Group median: 70,855,220 • 64.7%ile (≈ Median)
28,652 Detected genes Group median: 31,576 • 21.6%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 76.4%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

66.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 10.00
bar=donor   line=cohort median 		9.31 89.3%
CETP Lipid Metabolism 1.02
bar=donor   line=cohort median 		1.18 38.3%
SIRT6 Sirtuin Family 2.07
bar=donor   line=cohort median 		2.22 32.1%
SIRT1 Sirtuin Family 5.65
bar=donor   line=cohort median 		5.50 79.0%
SIRT3 Sirtuin Family 2.23
bar=donor   line=cohort median 		2.33 34.8%
IGF1R Insulin/IGF-1 Signaling 7.64
bar=donor   line=cohort median 		7.09 95.5%
KLOTHO Anti-aging 1.29
bar=donor   line=cohort median 		0.66 86.6%
IRS2 Insulin/IGF-1 Signaling 5.68
bar=donor   line=cohort median 		5.59 57.6%
TP53 Tumor Suppression 2.93
bar=donor   line=cohort median 		2.72 63.8%
SHC1 Signal Transduction 4.23
bar=donor   line=cohort median 		3.95 86.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 13.9 1,220,889
2 ENSG00000265150 ENSG00000265150 13.6 930,963
3 ENSG00000258486 ENSG00000258486 13.5 926,331
4 B2M ENSG00000166710 protein_coding 13.1 701,377
5 MALAT1 ENSG00000251562 lncRNA 12.9 600,615
6 ALAS2 ENSG00000158578 protein_coding 12.9 577,960
7 S100A9 ENSG00000163220 protein_coding 12.8 542,294
8 FCGR3B ENSG00000162747 protein_coding 12.8 533,528
9 AL355075.4 ENSG00000259001 lncRNA 12.5 443,849
10 NAMPT ENSG00000105835 protein_coding 12.3 398,617

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.4
bar=donor   line=cohort median 		11.8 11.8 24.3%
2 S100A9 protein_coding 12.8
bar=donor   line=cohort median 		13.1 13.1 28.4%
3 IL1B protein_coding 7.3
bar=donor   line=cohort median 		6.9 6.9 84.6%
4 CXCL8 protein_coding 7.6
bar=donor   line=cohort median 		7.6 7.6 53.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.5
bar=donor   line=cohort median 		4.0 4.0 12.0%
6 FCGR3B protein_coding 12.8
bar=donor   line=cohort median 		11.3 11.3 99.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.5
bar=donor   line=cohort median 		10.9 10.9 19.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 70.9%
9 CD3E protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 63.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.5
bar=donor   line=cohort median 		6.3 6.3 65.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.0
bar=donor   line=cohort median 		3.4 3.4 78.4%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 43.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.2
bar=donor   line=cohort median 		6.6 6.6 40.8%
14 HBA1 protein_coding 2.8
bar=donor   line=cohort median 		2.6 2.6 52.4%
15 HBA2 protein_coding 6.1
bar=donor   line=cohort median 		5.6 5.6 55.1%
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