GSM5528669

Dataset: gse182409 • Sample: T173 • Status: Pregnancy-stage cohort
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Quality Control Metrics

87,992,394 Total counts Group median: 70,855,220 • 87.3%ile (↑ High)
31,838 Detected genes Group median: 31,576 • 55.8%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 0.3%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

57.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.07
bar=donor   line=cohort median 		9.31 30.7%
CETP Lipid Metabolism 2.15
bar=donor   line=cohort median 		1.18 92.8%
SIRT6 Sirtuin Family 1.68
bar=donor   line=cohort median 		2.22 1.0%
SIRT1 Sirtuin Family 5.36
bar=donor   line=cohort median 		5.50 19.0%
SIRT3 Sirtuin Family 2.48
bar=donor   line=cohort median 		2.33 72.1%
IGF1R Insulin/IGF-1 Signaling 7.20
bar=donor   line=cohort median 		7.09 63.1%
KLOTHO Anti-aging 1.07
bar=donor   line=cohort median 		0.66 75.5%
IRS2 Insulin/IGF-1 Signaling 5.69
bar=donor   line=cohort median 		5.59 59.7%
TP53 Tumor Suppression 3.19
bar=donor   line=cohort median 		2.72 77.6%
SHC1 Signal Transduction 4.22
bar=donor   line=cohort median 		3.95 85.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.6 5,025,166
2 ENSG00000258486 ENSG00000258486 15.5 5,460,660
3 7SK ENSG00000202198 misc_RNA 14.5 2,582,088
4 ENSG00000138293 ENSG00000138293 14.2 1,347,884
5 ALAS2 ENSG00000158578 protein_coding 14.0 2,350,559
6 TENT5C ENSG00000183508 protein_coding 14.0 784,608
7 BNIP3L ENSG00000104765 protein_coding 13.4 1,138,017
8 HBG2 ENSG00000196565 protein_coding 13.3 375
9 SLC25A37 ENSG00000147454 protein_coding 13.2 527,945
10 EPB41 ENSG00000159023 protein_coding 13.2 593,805

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 10.2
bar=donor   line=cohort median 		11.8 11.8 0.3%
2 S100A9 protein_coding 11.4
bar=donor   line=cohort median 		13.1 13.1 0.3%
3 IL1B protein_coding 6.7
bar=donor   line=cohort median 		6.9 6.9 42.8%
4 CXCL8 protein_coding 7.2
bar=donor   line=cohort median 		7.6 7.6 38.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.9
bar=donor   line=cohort median 		4.0 4.0 72.3%
6 FCGR3B protein_coding 9.3
bar=donor   line=cohort median 		11.3 11.3 0.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.0
bar=donor   line=cohort median 		10.9 10.9 5.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.7
bar=donor   line=cohort median 		5.3 5.3 86.0%
9 CD3E protein_coding 4.2
bar=donor   line=cohort median 		2.6 2.6 98.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.5
bar=donor   line=cohort median 		6.3 6.3 99.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.0
bar=donor   line=cohort median 		3.4 3.4 30.5%
12 GNLY protein_coding 2.3
bar=donor   line=cohort median 		4.9 4.9 0.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.6
bar=donor   line=cohort median 		6.6 6.6 48.3%
14 HBA1 protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 56.5%
15 HBA2 protein_coding 6.4
bar=donor   line=cohort median 		5.6 5.6 58.6%
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