GSM5528672

Dataset: gse182409 • Sample: T176 • Status: Pregnancy-stage cohort
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Quality Control Metrics

99,669,168 Total counts Group median: 70,855,220 • 95.5%ile (↑ High)
33,036 Detected genes Group median: 31,576 • 82.5%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 49.0%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

42.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.41
bar=donor   line=cohort median 		9.31 56.9%
CETP Lipid Metabolism 0.46
bar=donor   line=cohort median 		1.18 10.0%
SIRT6 Sirtuin Family 2.23
bar=donor   line=cohort median 		2.22 50.7%
SIRT1 Sirtuin Family 5.36
bar=donor   line=cohort median 		5.50 18.3%
SIRT3 Sirtuin Family 2.24
bar=donor   line=cohort median 		2.33 36.9%
IGF1R Insulin/IGF-1 Signaling 7.54
bar=donor   line=cohort median 		7.09 91.4%
KLOTHO Anti-aging 1.06
bar=donor   line=cohort median 		0.66 73.5%
IRS2 Insulin/IGF-1 Signaling 5.56
bar=donor   line=cohort median 		5.59 43.8%
TP53 Tumor Suppression 1.86
bar=donor   line=cohort median 		2.72 5.2%
SHC1 Signal Transduction 3.85
bar=donor   line=cohort median 		3.95 36.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.4 3,678,081
2 7SK ENSG00000202198 misc_RNA 13.9 2,367,198
3 ENSG00000258486 ENSG00000258486 13.9 3,371,938
4 MALAT1 ENSG00000251562 lncRNA 13.8 1,020,772
5 S100A9 ENSG00000163220 protein_coding 12.9 1,317,510
6 B2M ENSG00000166710 protein_coding 12.7 944,036
7 AL355075.4 ENSG00000259001 lncRNA 12.6 1,008,817
8 ALAS2 ENSG00000158578 protein_coding 12.5 656,163
9 TENT5C ENSG00000183508 protein_coding 12.4 194,902
10 SLC25A37 ENSG00000147454 protein_coding 12.4 377,202

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.6
bar=donor   line=cohort median 		11.8 11.8 33.9%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median 		13.1 13.1 39.4%
3 IL1B protein_coding 5.8
bar=donor   line=cohort median 		6.9 6.9 5.1%
4 CXCL8 protein_coding 6.8
bar=donor   line=cohort median 		7.6 7.6 28.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 6.8
bar=donor   line=cohort median 		4.0 4.0 99.7%
6 FCGR3B protein_coding 10.8
bar=donor   line=cohort median 		11.3 11.3 12.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 55.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.6
bar=donor   line=cohort median 		5.3 5.3 2.4%
9 CD3E protein_coding 3.6
bar=donor   line=cohort median 		2.6 2.6 91.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.8
bar=donor   line=cohort median 		6.3 6.3 21.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 5.2
bar=donor   line=cohort median 		3.4 3.4 99.0%
12 GNLY protein_coding 5.5
bar=donor   line=cohort median 		4.9 4.9 83.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.5
bar=donor   line=cohort median 		6.6 6.6 44.9%
14 HBA1 protein_coding 1.1
bar=donor   line=cohort median 		2.6 2.6 31.8%
15 HBA2 protein_coding 3.1
bar=donor   line=cohort median 		5.6 5.6 18.8%
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