GSM5528673

Dataset: gse182409 • Sample: T177 • Status: Pregnancy-stage cohort
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Quality Control Metrics

89,760,974 Total counts Group median: 70,855,220 • 89.4%ile (↑ High)
30,704 Detected genes Group median: 31,576 • 40.8%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 91.4%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

75.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.54
bar=donor   line=cohort median 		9.31 67.2%
CETP Lipid Metabolism 1.72
bar=donor   line=cohort median 		1.18 81.0%
SIRT6 Sirtuin Family 2.38
bar=donor   line=cohort median 		2.22 74.8%
SIRT1 Sirtuin Family 5.48
bar=donor   line=cohort median 		5.50 42.4%
SIRT3 Sirtuin Family 2.58
bar=donor   line=cohort median 		2.33 85.2%
IGF1R Insulin/IGF-1 Signaling 7.74
bar=donor   line=cohort median 		7.09 99.0%
KLOTHO Anti-aging 0.43
bar=donor   line=cohort median 		0.66 27.2%
IRS2 Insulin/IGF-1 Signaling 6.31
bar=donor   line=cohort median 		5.59 95.5%
TP53 Tumor Suppression 3.64
bar=donor   line=cohort median 		2.72 94.1%
SHC1 Signal Transduction 4.21
bar=donor   line=cohort median 		3.95 84.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.2 1,927,186
2 ENSG00000258486 ENSG00000258486 15.1 1,323,294
3 7SK ENSG00000202198 misc_RNA 14.6 1,325,729
4 MALAT1 ENSG00000251562 lncRNA 14.0 1,294,676
5 AL355075.4 ENSG00000259001 lncRNA 13.5 563,508
6 S100A9 ENSG00000163220 protein_coding 13.3 698,524
7 B2M ENSG00000166710 protein_coding 13.3 600,671
8 NEAT1 ENSG00000245532 lncRNA 12.7 284,101
9 NAMPT ENSG00000105835 protein_coding 12.7 367,135
10 BNIP3L ENSG00000104765 protein_coding 12.4 376,729

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 80.5%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 75.7%
3 IL1B protein_coding 7.2
bar=donor   line=cohort median 		6.9 6.9 76.4%
4 CXCL8 protein_coding 6.3
bar=donor   line=cohort median 		7.6 7.6 14.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.9
bar=donor   line=cohort median 		4.0 4.0 75.0%
6 FCGR3B protein_coding 11.5
bar=donor   line=cohort median 		11.3 11.3 64.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.1
bar=donor   line=cohort median 		10.9 10.9 67.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.7
bar=donor   line=cohort median 		5.3 5.3 6.5%
9 CD3E protein_coding 2.7
bar=donor   line=cohort median 		2.6 2.6 51.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.0
bar=donor   line=cohort median 		6.3 6.3 27.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.4
bar=donor   line=cohort median 		3.4 3.4 49.0%
12 GNLY protein_coding 5.8
bar=donor   line=cohort median 		4.9 4.9 92.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.4
bar=donor   line=cohort median 		6.6 6.6 22.9%
14 HBA1 protein_coding -0.4
bar=donor   line=cohort median 		2.6 2.6 15.4%
15 HBA2 protein_coding 2.5
bar=donor   line=cohort median 		5.6 5.6 7.2%
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