GSM5528674

Dataset: gse182409 • Sample: T178 • Status: Pregnancy-stage cohort
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Quality Control Metrics

64,290,278 Total counts Group median: 70,855,220 • 31.8%ile (≈ Median)
32,395 Detected genes Group median: 31,576 • 70.9%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 36.0%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

43.2Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.16
bar=donor   line=cohort median 		9.31 38.3%
CETP Lipid Metabolism 0.84
bar=donor   line=cohort median 		1.18 23.1%
SIRT6 Sirtuin Family 2.07
bar=donor   line=cohort median 		2.22 30.7%
SIRT1 Sirtuin Family 5.41
bar=donor   line=cohort median 		5.50 27.2%
SIRT3 Sirtuin Family 2.00
bar=donor   line=cohort median 		2.33 9.3%
IGF1R Insulin/IGF-1 Signaling 7.67
bar=donor   line=cohort median 		7.09 96.9%
KLOTHO Anti-aging 0.66
bar=donor   line=cohort median 		0.66 49.3%
IRS2 Insulin/IGF-1 Signaling 5.88
bar=donor   line=cohort median 		5.59 79.0%
TP53 Tumor Suppression 2.73
bar=donor   line=cohort median 		2.72 51.4%
SHC1 Signal Transduction 3.81
bar=donor   line=cohort median 		3.95 27.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.1 1,996,282
2 7SK ENSG00000202198 misc_RNA 14.8 1,445,887
3 ENSG00000265150 ENSG00000265150 14.5 2,083,727
4 MALAT1 ENSG00000251562 lncRNA 13.8 920,210
5 AL355075.4 ENSG00000259001 lncRNA 13.3 682,931
6 B2M ENSG00000166710 protein_coding 12.9 571,912
7 S100A9 ENSG00000163220 protein_coding 12.9 588,890
8 NEAT1 ENSG00000245532 lncRNA 12.4 373,593
9 ALAS2 ENSG00000158578 protein_coding 12.4 293,026
10 EEF1A1 ENSG00000156508 protein_coding 12.3 240,874

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 53.1%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median 		13.1 13.1 35.3%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 66.8%
4 CXCL8 protein_coding 7.1
bar=donor   line=cohort median 		7.6 7.6 36.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 6.4
bar=donor   line=cohort median 		4.0 4.0 96.9%
6 FCGR3B protein_coding 9.9
bar=donor   line=cohort median 		11.3 11.3 1.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.3
bar=donor   line=cohort median 		10.9 10.9 82.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.6
bar=donor   line=cohort median 		5.3 5.3 76.4%
9 CD3E protein_coding 3.2
bar=donor   line=cohort median 		2.6 2.6 81.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median 		6.3 6.3 54.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.3
bar=donor   line=cohort median 		3.4 3.4 41.4%
12 GNLY protein_coding 4.0
bar=donor   line=cohort median 		4.9 4.9 8.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.6
bar=donor   line=cohort median 		6.6 6.6 49.0%
14 HBA1 protein_coding 0.7
bar=donor   line=cohort median 		2.6 2.6 29.1%
15 HBA2 protein_coding 4.0
bar=donor   line=cohort median 		5.6 5.6 33.9%
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