GSM5528675

Dataset: gse182409 • Sample: T179 • Status: Pregnancy-stage cohort
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Quality Control Metrics

52,705,041 Total counts Group median: 70,855,220 • 11.3%ile (↓ Low)
29,576 Detected genes Group median: 31,576 • 32.5%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 67.5%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

43.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.94
bar=donor   line=cohort median 		9.31 19.7%
CETP Lipid Metabolism 0.84
bar=donor   line=cohort median 		1.18 24.5%
SIRT6 Sirtuin Family 1.95
bar=donor   line=cohort median 		2.22 19.7%
SIRT1 Sirtuin Family 5.49
bar=donor   line=cohort median 		5.50 45.9%
SIRT3 Sirtuin Family 2.12
bar=donor   line=cohort median 		2.33 20.3%
IGF1R Insulin/IGF-1 Signaling 7.28
bar=donor   line=cohort median 		7.09 74.8%
KLOTHO Anti-aging 1.19
bar=donor   line=cohort median 		0.66 83.1%
IRS2 Insulin/IGF-1 Signaling 5.81
bar=donor   line=cohort median 		5.59 69.3%
TP53 Tumor Suppression 3.02
bar=donor   line=cohort median 		2.72 70.0%
SHC1 Signal Transduction 3.50
bar=donor   line=cohort median 		3.95 2.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.2 1,542,436
2 ENSG00000258486 ENSG00000258486 14.1 1,949,712
3 ENSG00000265150 ENSG00000265150 14.0 1,219,547
4 ALAS2 ENSG00000158578 protein_coding 13.8 296,116
5 HBB ENSG00000244734 protein_coding 13.6 5,274
6 B2M ENSG00000166710 protein_coding 13.3 415,403
7 AL355075.4 ENSG00000259001 lncRNA 13.2 563,197
8 S100A9 ENSG00000163220 protein_coding 13.1 410,864
9 MALAT1 ENSG00000251562 lncRNA 13.1 757,625
10 SLC25A37 ENSG00000147454 protein_coding 12.7 234,036

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.0
bar=donor   line=cohort median 		11.8 11.8 67.5%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 52.4%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 57.2%
4 CXCL8 protein_coding 6.8
bar=donor   line=cohort median 		7.6 7.6 29.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.7
bar=donor   line=cohort median 		4.0 4.0 93.5%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 46.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.1
bar=donor   line=cohort median 		10.9 10.9 64.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.4
bar=donor   line=cohort median 		5.3 5.3 65.4%
9 CD3E protein_coding 2.5
bar=donor   line=cohort median 		2.6 2.6 43.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.2
bar=donor   line=cohort median 		6.3 6.3 46.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.5
bar=donor   line=cohort median 		3.4 3.4 90.8%
12 GNLY protein_coding 5.6
bar=donor   line=cohort median 		4.9 4.9 85.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 13.6
bar=donor   line=cohort median 		6.6 6.6 98.3%
14 HBA1 protein_coding 8.2
bar=donor   line=cohort median 		2.6 2.6 99.0%
15 HBA2 protein_coding 11.7
bar=donor   line=cohort median 		5.6 5.6 98.3%
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