GSM5528676

Dataset: gse182409 • Sample: T180 • Status: Pregnancy-stage cohort
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Quality Control Metrics

80,818,704 Total counts Group median: 70,855,220 • 71.6%ile (≈ Median)
28,648 Detected genes Group median: 31,576 • 20.9%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 88.7%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

51.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.48
bar=donor   line=cohort median 		9.31 65.2%
CETP Lipid Metabolism 0.87
bar=donor   line=cohort median 		1.18 27.2%
SIRT6 Sirtuin Family 2.10
bar=donor   line=cohort median 		2.22 35.5%
SIRT1 Sirtuin Family 5.36
bar=donor   line=cohort median 		5.50 17.6%
SIRT3 Sirtuin Family 2.52
bar=donor   line=cohort median 		2.33 79.0%
IGF1R Insulin/IGF-1 Signaling 6.89
bar=donor   line=cohort median 		7.09 31.4%
KLOTHO Anti-aging 1.21
bar=donor   line=cohort median 		0.66 84.5%
IRS2 Insulin/IGF-1 Signaling 5.06
bar=donor   line=cohort median 		5.59 12.8%
TP53 Tumor Suppression 3.21
bar=donor   line=cohort median 		2.72 80.3%
SHC1 Signal Transduction 4.21
bar=donor   line=cohort median 		3.95 83.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.3 1,184,839
2 ENSG00000258486 ENSG00000258486 14.2 1,117,127
3 ENSG00000265150 ENSG00000265150 14.1 1,043,206
4 MALAT1 ENSG00000251562 lncRNA 13.9 539,346
5 S100A9 ENSG00000163220 protein_coding 13.1 569,636
6 B2M ENSG00000166710 protein_coding 13.0 637,275
7 AL355075.4 ENSG00000259001 lncRNA 12.9 586,956
8 ALAS2 ENSG00000158578 protein_coding 12.6 900,562
9 NEAT1 ENSG00000245532 lncRNA 12.6 64,330
10 NAMPT ENSG00000105835 protein_coding 12.3 285,130

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 53.8%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 45.5%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 64.0%
4 CXCL8 protein_coding 6.5
bar=donor   line=cohort median 		7.6 7.6 16.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.9
bar=donor   line=cohort median 		4.0 4.0 74.3%
6 FCGR3B protein_coding 11.1
bar=donor   line=cohort median 		11.3 11.3 33.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.6
bar=donor   line=cohort median 		10.9 10.9 27.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 48.3%
9 CD3E protein_coding 3.2
bar=donor   line=cohort median 		2.6 2.6 78.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.8
bar=donor   line=cohort median 		6.3 6.3 81.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.9
bar=donor   line=cohort median 		3.4 3.4 73.6%
12 GNLY protein_coding 5.4
bar=donor   line=cohort median 		4.9 4.9 81.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.3
bar=donor   line=cohort median 		6.6 6.6 20.9%
14 HBA1 protein_coding -0.8
bar=donor   line=cohort median 		2.6 2.6 4.5%
15 HBA2 protein_coding 1.8
bar=donor   line=cohort median 		5.6 5.6 1.0%
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