GSM5528678

Dataset: gse182409 • Sample: T182 • Status: Pregnancy-stage cohort
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Quality Control Metrics

55,565,672 Total counts Group median: 70,855,220 • 15.4%ile (↓ Low)
31,580 Detected genes Group median: 31,576 • 50.3%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 31.8%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

46.4Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.29
bar=donor   line=cohort median 		9.31 49.3%
CETP Lipid Metabolism 0.03
bar=donor   line=cohort median 		1.18 2.4%
SIRT6 Sirtuin Family 2.20
bar=donor   line=cohort median 		2.22 47.9%
SIRT1 Sirtuin Family 5.32
bar=donor   line=cohort median 		5.50 11.4%
SIRT3 Sirtuin Family 2.05
bar=donor   line=cohort median 		2.33 12.8%
IGF1R Insulin/IGF-1 Signaling 7.94
bar=donor   line=cohort median 		7.09 99.7%
KLOTHO Anti-aging 0.78
bar=donor   line=cohort median 		0.66 58.3%
IRS2 Insulin/IGF-1 Signaling 5.59
bar=donor   line=cohort median 		5.59 49.3%
TP53 Tumor Suppression 3.07
bar=donor   line=cohort median 		2.72 72.1%
SHC1 Signal Transduction 4.02
bar=donor   line=cohort median 		3.95 61.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.8 2,188,922
2 ENSG00000265150 ENSG00000265150 15.8 2,173,914
3 7SK ENSG00000202198 misc_RNA 14.3 1,253,322
4 MALAT1 ENSG00000251562 lncRNA 13.7 663,303
5 B2M ENSG00000166710 protein_coding 13.2 360,785
6 AL355075.4 ENSG00000259001 lncRNA 13.1 376,305
7 ALAS2 ENSG00000158578 protein_coding 12.7 700,131
8 S100A9 ENSG00000163220 protein_coding 12.5 350,905
9 NEAT1 ENSG00000245532 lncRNA 12.3 254,565
10 NAMPT ENSG00000105835 protein_coding 12.3 227,507

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.2
bar=donor   line=cohort median 		11.8 11.8 13.4%
2 S100A9 protein_coding 12.5
bar=donor   line=cohort median 		13.1 13.1 12.7%
3 IL1B protein_coding 6.6
bar=donor   line=cohort median 		6.9 6.9 31.2%
4 CXCL8 protein_coding 5.5
bar=donor   line=cohort median 		7.6 7.6 7.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.7
bar=donor   line=cohort median 		4.0 4.0 16.8%
6 FCGR3B protein_coding 11.4
bar=donor   line=cohort median 		11.3 11.3 53.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.6
bar=donor   line=cohort median 		10.9 10.9 26.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 41.4%
9 CD3E protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 62.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median 		6.3 6.3 86.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.4
bar=donor   line=cohort median 		3.4 3.4 6.5%
12 GNLY protein_coding 3.7
bar=donor   line=cohort median 		4.9 4.9 3.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.7
bar=donor   line=cohort median 		6.6 6.6 7.9%
14 HBA1 protein_coding -0.3
bar=donor   line=cohort median 		2.6 2.6 18.8%
15 HBA2 protein_coding 3.3
bar=donor   line=cohort median 		5.6 5.6 24.3%
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