GSM5528679

Dataset: gse182409 • Sample: T183 • Status: Pregnancy-stage cohort
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Quality Control Metrics

43,302,588 Total counts Group median: 70,855,220 • 2.4%ile (↓ Low)
31,347 Detected genes Group median: 31,576 • 45.5%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 23.6%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

34.8Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.95
bar=donor   line=cohort median 		9.31 21.0%
CETP Lipid Metabolism 1.26
bar=donor   line=cohort median 		1.18 55.5%
SIRT6 Sirtuin Family 1.91
bar=donor   line=cohort median 		2.22 14.8%
SIRT1 Sirtuin Family 5.60
bar=donor   line=cohort median 		5.50 70.0%
SIRT3 Sirtuin Family 2.33
bar=donor   line=cohort median 		2.33 50.0%
IGF1R Insulin/IGF-1 Signaling 6.94
bar=donor   line=cohort median 		7.09 36.9%
KLOTHO Anti-aging 0.56
bar=donor   line=cohort median 		0.66 41.0%
IRS2 Insulin/IGF-1 Signaling 5.14
bar=donor   line=cohort median 		5.59 16.2%
TP53 Tumor Suppression 2.53
bar=donor   line=cohort median 		2.72 39.0%
SHC1 Signal Transduction 3.53
bar=donor   line=cohort median 		3.95 3.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.4 847,424
2 ENSG00000265150 ENSG00000265150 13.6 2,363,832
3 ENSG00000258486 ENSG00000258486 13.5 2,433,655
4 B2M ENSG00000166710 protein_coding 13.5 382,784
5 MALAT1 ENSG00000251562 lncRNA 13.3 564,859
6 S100A9 ENSG00000163220 protein_coding 13.1 246,511
7 AL355075.4 ENSG00000259001 lncRNA 12.9 369,704
8 FCGR3B ENSG00000162747 protein_coding 12.6 108,275
9 NAMPT ENSG00000105835 protein_coding 12.4 211,856
10 SOD2 ENSG00000112096 protein_coding 12.2 149,988

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.8
bar=donor   line=cohort median 		11.8 11.8 49.0%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 47.6%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 61.3%
4 CXCL8 protein_coding 7.8
bar=donor   line=cohort median 		7.6 7.6 57.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.5
bar=donor   line=cohort median 		4.0 4.0 36.6%
6 FCGR3B protein_coding 12.6
bar=donor   line=cohort median 		11.3 11.3 99.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 73.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.5
bar=donor   line=cohort median 		5.3 5.3 1.7%
9 CD3E protein_coding 2.7
bar=donor   line=cohort median 		2.6 2.6 52.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.9
bar=donor   line=cohort median 		6.3 6.3 25.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.9
bar=donor   line=cohort median 		3.4 3.4 72.9%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 42.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.2
bar=donor   line=cohort median 		6.6 6.6 42.1%
14 HBA1 protein_coding 2.0
bar=donor   line=cohort median 		2.6 2.6 42.8%
15 HBA2 protein_coding 5.1
bar=donor   line=cohort median 		5.6 5.6 42.8%
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