GSM5528681

Dataset: gse182409 • Sample: T185 • Status: Pregnancy-stage cohort
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Quality Control Metrics

71,138,852 Total counts Group median: 70,855,220 • 51.0%ile (≈ Median)
33,420 Detected genes Group median: 31,576 • 89.0%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 55.8%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

44.4Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.23
bar=donor   line=cohort median 		9.31 47.2%
CETP Lipid Metabolism 0.89
bar=donor   line=cohort median 		1.18 30.0%
SIRT6 Sirtuin Family 1.70
bar=donor   line=cohort median 		2.22 1.7%
SIRT1 Sirtuin Family 5.34
bar=donor   line=cohort median 		5.50 14.8%
SIRT3 Sirtuin Family 2.56
bar=donor   line=cohort median 		2.33 82.4%
IGF1R Insulin/IGF-1 Signaling 7.21
bar=donor   line=cohort median 		7.09 65.9%
KLOTHO Anti-aging 0.72
bar=donor   line=cohort median 		0.66 54.8%
IRS2 Insulin/IGF-1 Signaling 5.46
bar=donor   line=cohort median 		5.59 36.2%
TP53 Tumor Suppression 3.02
bar=donor   line=cohort median 		2.72 70.7%
SHC1 Signal Transduction 3.87
bar=donor   line=cohort median 		3.95 40.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.2 1,732,119
2 ENSG00000258486 ENSG00000258486 15.2 2,591,441
3 7SK ENSG00000202198 misc_RNA 14.3 1,475,069
4 MALAT1 ENSG00000251562 lncRNA 13.8 970,987
5 B2M ENSG00000166710 protein_coding 13.3 609,740
6 ALAS2 ENSG00000158578 protein_coding 13.1 355,459
7 AL355075.4 ENSG00000259001 lncRNA 12.8 609,203
8 S100A9 ENSG00000163220 protein_coding 12.6 498,947
9 SLC25A37 ENSG00000147454 protein_coding 12.3 291,686
10 NEAT1 ENSG00000245532 lncRNA 12.2 333,761

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.3
bar=donor   line=cohort median 		11.8 11.8 17.5%
2 S100A9 protein_coding 12.6
bar=donor   line=cohort median 		13.1 13.1 16.1%
3 IL1B protein_coding 6.8
bar=donor   line=cohort median 		6.9 6.9 48.3%
4 CXCL8 protein_coding 5.5
bar=donor   line=cohort median 		7.6 7.6 5.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 1.1
bar=donor   line=cohort median 		4.0 4.0 1.0%
6 FCGR3B protein_coding 12.0
bar=donor   line=cohort median 		11.3 11.3 92.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.7
bar=donor   line=cohort median 		10.9 10.9 32.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 55.8%
9 CD3E protein_coding 3.5
bar=donor   line=cohort median 		2.6 2.6 88.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.4
bar=donor   line=cohort median 		6.3 6.3 56.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.5
bar=donor   line=cohort median 		3.4 3.4 52.4%
12 GNLY protein_coding 4.5
bar=donor   line=cohort median 		4.9 4.9 29.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.2
bar=donor   line=cohort median 		6.6 6.6 80.5%
14 HBA1 protein_coding 3.7
bar=donor   line=cohort median 		2.6 2.6 62.0%
15 HBA2 protein_coding 6.3
bar=donor   line=cohort median 		5.6 5.6 56.5%
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