GSM5528684

Dataset: gse182409 • Sample: T188 • Status: Pregnancy-stage cohort
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Quality Control Metrics

53,064,380 Total counts Group median: 70,855,220 • 12.7%ile (↓ Low)
33,709 Detected genes Group median: 31,576 • 95.5%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 81.2%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

32.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.61
bar=donor   line=cohort median 		9.31 5.9%
CETP Lipid Metabolism 1.88
bar=donor   line=cohort median 		1.18 87.9%
SIRT6 Sirtuin Family 1.77
bar=donor   line=cohort median 		2.22 5.2%
SIRT1 Sirtuin Family 5.28
bar=donor   line=cohort median 		5.50 5.9%
SIRT3 Sirtuin Family 2.25
bar=donor   line=cohort median 		2.33 38.3%
IGF1R Insulin/IGF-1 Signaling 6.74
bar=donor   line=cohort median 		7.09 19.0%
KLOTHO Anti-aging 0.56
bar=donor   line=cohort median 		0.66 38.3%
IRS2 Insulin/IGF-1 Signaling 5.30
bar=donor   line=cohort median 		5.59 25.9%
TP53 Tumor Suppression 3.09
bar=donor   line=cohort median 		2.72 73.5%
SHC1 Signal Transduction 3.81
bar=donor   line=cohort median 		3.95 26.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.2 1,858,592
2 ENSG00000258486 ENSG00000258486 15.0 1,771,105
3 7SK ENSG00000202198 misc_RNA 14.4 1,166,191
4 MALAT1 ENSG00000251562 lncRNA 13.9 800,310
5 ALAS2 ENSG00000158578 protein_coding 13.8 293,278
6 S100A9 ENSG00000163220 protein_coding 13.3 268,852
7 B2M ENSG00000166710 protein_coding 13.2 430,790
8 AL355075.4 ENSG00000259001 lncRNA 13.1 615,069
9 SLC25A37 ENSG00000147454 protein_coding 12.9 396,787
10 NAMPT ENSG00000105835 protein_coding 12.5 209,743

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median 		11.8 11.8 77.7%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 70.2%
3 IL1B protein_coding 7.6
bar=donor   line=cohort median 		6.9 6.9 93.5%
4 CXCL8 protein_coding 8.2
bar=donor   line=cohort median 		7.6 7.6 73.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.4
bar=donor   line=cohort median 		4.0 4.0 33.2%
6 FCGR3B protein_coding 11.4
bar=donor   line=cohort median 		11.3 11.3 54.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 37.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.4
bar=donor   line=cohort median 		5.3 5.3 64.0%
9 CD3E protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 62.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.5
bar=donor   line=cohort median 		6.3 6.3 66.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median 		3.4 3.4 66.1%
12 GNLY protein_coding 4.3
bar=donor   line=cohort median 		4.9 4.9 19.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.6
bar=donor   line=cohort median 		6.6 6.6 60.6%
14 HBA1 protein_coding 1.9
bar=donor   line=cohort median 		2.6 2.6 42.1%
15 HBA2 protein_coding 4.6
bar=donor   line=cohort median 		5.6 5.6 36.6%
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