GSM5528685

Dataset: gse182409 • Sample: T189 • Status: Pregnancy-stage cohort
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Quality Control Metrics

32,195,296 Total counts Group median: 70,855,220 • 0.3%ile (↓ Low)
27,561 Detected genes Group median: 31,576 • 12.0%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 11.3%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

59.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.31
bar=donor   line=cohort median 		9.31 50.0%
CETP Lipid Metabolism 1.64
bar=donor   line=cohort median 		1.18 79.0%
SIRT6 Sirtuin Family 2.65
bar=donor   line=cohort median 		2.22 94.1%
SIRT1 Sirtuin Family 4.90
bar=donor   line=cohort median 		5.50 0.3%
SIRT3 Sirtuin Family 3.05
bar=donor   line=cohort median 		2.33 98.3%
IGF1R Insulin/IGF-1 Signaling 7.20
bar=donor   line=cohort median 		7.09 61.7%
KLOTHO Anti-aging 0.49
bar=donor   line=cohort median 		0.66 32.8%
IRS2 Insulin/IGF-1 Signaling 5.59
bar=donor   line=cohort median 		5.59 50.0%
TP53 Tumor Suppression 2.98
bar=donor   line=cohort median 		2.72 68.6%
SHC1 Signal Transduction 4.01
bar=donor   line=cohort median 		3.95 59.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.8 1,034,599
2 ENSG00000258486 ENSG00000258486 14.7 905,446
3 MALAT1 ENSG00000251562 lncRNA 14.0 427,971
4 7SK ENSG00000202198 misc_RNA 14.0 611,534
5 AL355075.4 ENSG00000259001 lncRNA 12.9 252,203
6 B2M ENSG00000166710 protein_coding 12.9 260,704
7 BNIP3L ENSG00000104765 protein_coding 12.6 130,686
8 S100A9 ENSG00000163220 protein_coding 12.5 277,264
9 ALAS2 ENSG00000158578 protein_coding 12.4 396,700
10 NEAT1 ENSG00000245532 lncRNA 12.4 162,740

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.4
bar=donor   line=cohort median 		11.8 11.8 19.5%
2 S100A9 protein_coding 12.5
bar=donor   line=cohort median 		13.1 13.1 9.2%
3 IL1B protein_coding 6.3
bar=donor   line=cohort median 		6.9 6.9 18.8%
4 CXCL8 protein_coding 5.4
bar=donor   line=cohort median 		7.6 7.6 5.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.3
bar=donor   line=cohort median 		4.0 4.0 86.0%
6 FCGR3B protein_coding 10.7
bar=donor   line=cohort median 		11.3 11.3 12.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.4
bar=donor   line=cohort median 		10.9 10.9 17.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 51.7%
9 CD3E protein_coding 3.0
bar=donor   line=cohort median 		2.6 2.6 68.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.0
bar=donor   line=cohort median 		6.3 6.3 27.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.5
bar=donor   line=cohort median 		3.4 3.4 92.8%
12 GNLY protein_coding 6.2
bar=donor   line=cohort median 		4.9 4.9 97.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.9
bar=donor   line=cohort median 		6.6 6.6 12.0%
14 HBA1 protein_coding -0.4
bar=donor   line=cohort median 		2.6 2.6 14.7%
15 HBA2 protein_coding 2.6
bar=donor   line=cohort median 		5.6 5.6 8.6%
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