GSM5528686

Dataset: gse182409 • Sample: T190 • Status: Pregnancy-stage cohort
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Quality Control Metrics

77,792,503 Total counts Group median: 70,855,220 • 65.4%ile (≈ Median)
32,066 Detected genes Group median: 31,576 • 60.6%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 96.9%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

57.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.13
bar=donor   line=cohort median 		9.31 35.5%
CETP Lipid Metabolism 1.12
bar=donor   line=cohort median 		1.18 43.8%
SIRT6 Sirtuin Family 1.99
bar=donor   line=cohort median 		2.22 22.4%
SIRT1 Sirtuin Family 5.53
bar=donor   line=cohort median 		5.50 59.0%
SIRT3 Sirtuin Family 2.62
bar=donor   line=cohort median 		2.33 87.9%
IGF1R Insulin/IGF-1 Signaling 7.46
bar=donor   line=cohort median 		7.09 88.6%
KLOTHO Anti-aging -0.03
bar=donor   line=cohort median 		0.66 12.1%
IRS2 Insulin/IGF-1 Signaling 5.81
bar=donor   line=cohort median 		5.59 70.7%
TP53 Tumor Suppression 3.25
bar=donor   line=cohort median 		2.72 82.4%
SHC1 Signal Transduction 4.09
bar=donor   line=cohort median 		3.95 70.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.7 2,378,690
2 ENSG00000258486 ENSG00000258486 15.5 2,291,444
3 7SK ENSG00000202198 misc_RNA 14.6 1,339,526
4 MALAT1 ENSG00000251562 lncRNA 13.8 1,346,080
5 AL355075.4 ENSG00000259001 lncRNA 13.1 653,656
6 S100A9 ENSG00000163220 protein_coding 13.1 486,356
7 B2M ENSG00000166710 protein_coding 13.1 643,321
8 NEAT1 ENSG00000245532 lncRNA 12.9 438,827
9 NAMPT ENSG00000105835 protein_coding 12.4 291,778
10 SORL1 ENSG00000137642 protein_coding 12.2 329,595

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.8
bar=donor   line=cohort median 		11.8 11.8 50.3%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 49.7%
3 IL1B protein_coding 6.7
bar=donor   line=cohort median 		6.9 6.9 44.9%
4 CXCL8 protein_coding 6.8
bar=donor   line=cohort median 		7.6 7.6 23.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.3
bar=donor   line=cohort median 		4.0 4.0 29.1%
6 FCGR3B protein_coding 11.8
bar=donor   line=cohort median 		11.3 11.3 82.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 9.8
bar=donor   line=cohort median 		10.9 10.9 2.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 34.6%
9 CD3E protein_coding 2.6
bar=donor   line=cohort median 		2.6 2.6 49.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.1
bar=donor   line=cohort median 		6.3 6.3 40.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.5
bar=donor   line=cohort median 		3.4 3.4 54.5%
12 GNLY protein_coding 5.7
bar=donor   line=cohort median 		4.9 4.9 89.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.9
bar=donor   line=cohort median 		6.6 6.6 76.4%
14 HBA1 protein_coding 4.0
bar=donor   line=cohort median 		2.6 2.6 66.1%
15 HBA2 protein_coding 7.3
bar=donor   line=cohort median 		5.6 5.6 67.5%
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