GSM5528687

Dataset: gse182409 • Sample: T191 • Status: Pregnancy-stage cohort
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Quality Control Metrics

80,493,148 Total counts Group median: 70,855,220 • 70.9%ile (≈ Median)
34,235 Detected genes Group median: 31,576 • 96.9%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 80.5%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

58.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.56
bar=donor   line=cohort median 		9.31 3.1%
CETP Lipid Metabolism 1.62
bar=donor   line=cohort median 		1.18 75.5%
SIRT6 Sirtuin Family 2.33
bar=donor   line=cohort median 		2.22 67.9%
SIRT1 Sirtuin Family 5.35
bar=donor   line=cohort median 		5.50 16.2%
SIRT3 Sirtuin Family 2.43
bar=donor   line=cohort median 		2.33 66.6%
IGF1R Insulin/IGF-1 Signaling 7.64
bar=donor   line=cohort median 		7.09 96.2%
KLOTHO Anti-aging 0.93
bar=donor   line=cohort median 		0.66 67.2%
IRS2 Insulin/IGF-1 Signaling 5.75
bar=donor   line=cohort median 		5.59 63.8%
TP53 Tumor Suppression 2.82
bar=donor   line=cohort median 		2.72 58.3%
SHC1 Signal Transduction 4.13
bar=donor   line=cohort median 		3.95 74.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.2 3,656,072
2 7SK ENSG00000202198 misc_RNA 14.6 1,951,623
3 ENSG00000265150 ENSG00000265150 14.3 4,089,999
4 MALAT1 ENSG00000251562 lncRNA 13.7 1,146,652
5 ALAS2 ENSG00000158578 protein_coding 13.6 230,492
6 AL355075.4 ENSG00000259001 lncRNA 13.5 706,574
7 B2M ENSG00000166710 protein_coding 13.5 672,939
8 SLC25A37 ENSG00000147454 protein_coding 12.8 247,361
9 S100A9 ENSG00000163220 protein_coding 12.5 699,109
10 ADIPOR1 ENSG00000159346 protein_coding 12.3 179,976

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.2
bar=donor   line=cohort median 		11.8 11.8 14.0%
2 S100A9 protein_coding 12.5
bar=donor   line=cohort median 		13.1 13.1 10.6%
3 IL1B protein_coding 7.6
bar=donor   line=cohort median 		6.9 6.9 94.2%
4 CXCL8 protein_coding 7.3
bar=donor   line=cohort median 		7.6 7.6 41.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.6
bar=donor   line=cohort median 		4.0 4.0 16.1%
6 FCGR3B protein_coding 11.4
bar=donor   line=cohort median 		11.3 11.3 55.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.2
bar=donor   line=cohort median 		10.9 10.9 12.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.7
bar=donor   line=cohort median 		5.3 5.3 81.8%
9 CD3E protein_coding 2.6
bar=donor   line=cohort median 		2.6 2.6 50.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median 		6.3 6.3 85.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.0
bar=donor   line=cohort median 		3.4 3.4 29.8%
12 GNLY protein_coding 4.7
bar=donor   line=cohort median 		4.9 4.9 33.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.9
bar=donor   line=cohort median 		6.6 6.6 66.1%
14 HBA1 protein_coding 5.9
bar=donor   line=cohort median 		2.6 2.6 83.9%
15 HBA2 protein_coding 8.4
bar=donor   line=cohort median 		5.6 5.6 80.5%
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