GSM5528688

Dataset: gse182409 • Sample: T192 • Status: Pregnancy-stage cohort
◂ Prev All Donors Next ▸

Quality Control Metrics

44,777,436 Total counts Group median: 70,855,220 • 3.8%ile (↓ Low)
25,745 Detected genes Group median: 31,576 • 1.7%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 17.5%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

41.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.34
bar=donor   line=cohort median 		9.31 50.7%
CETP Lipid Metabolism 1.84
bar=donor   line=cohort median 		1.18 86.6%
SIRT6 Sirtuin Family 2.53
bar=donor   line=cohort median 		2.22 89.3%
SIRT1 Sirtuin Family 5.45
bar=donor   line=cohort median 		5.50 34.8%
SIRT3 Sirtuin Family 2.22
bar=donor   line=cohort median 		2.33 29.3%
IGF1R Insulin/IGF-1 Signaling 6.91
bar=donor   line=cohort median 		7.09 34.1%
KLOTHO Anti-aging -0.11
bar=donor   line=cohort median 		0.66 7.9%
IRS2 Insulin/IGF-1 Signaling 4.95
bar=donor   line=cohort median 		5.59 11.4%
TP53 Tumor Suppression 2.92
bar=donor   line=cohort median 		2.72 63.1%
SHC1 Signal Transduction 3.65
bar=donor   line=cohort median 		3.95 10.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.0 756,583
2 ENSG00000258486 ENSG00000258486 14.8 1,429,869
3 7SK ENSG00000202198 misc_RNA 14.1 955,828
4 MALAT1 ENSG00000251562 lncRNA 13.5 503,775
5 B2M ENSG00000166710 protein_coding 13.0 432,050
6 AL355075.4 ENSG00000259001 lncRNA 12.9 453,067
7 ALAS2 ENSG00000158578 protein_coding 12.9 462,934
8 S100A9 ENSG00000163220 protein_coding 12.7 221,209
9 EEF1A1 ENSG00000156508 protein_coding 12.4 185,209
10 NAMPT ENSG00000105835 protein_coding 11.9 169,628

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.4
bar=donor   line=cohort median 		11.8 11.8 25.7%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 20.2%
3 IL1B protein_coding 6.1
bar=donor   line=cohort median 		6.9 6.9 12.7%
4 CXCL8 protein_coding 7.0
bar=donor   line=cohort median 		7.6 7.6 34.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.7
bar=donor   line=cohort median 		4.0 4.0 92.1%
6 FCGR3B protein_coding 10.6
bar=donor   line=cohort median 		11.3 11.3 9.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 40.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 6.1
bar=donor   line=cohort median 		5.3 5.3 97.6%
9 CD3E protein_coding 3.2
bar=donor   line=cohort median 		2.6 2.6 80.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.4
bar=donor   line=cohort median 		6.3 6.3 59.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.6
bar=donor   line=cohort median 		3.4 3.4 94.9%
12 GNLY protein_coding 5.1
bar=donor   line=cohort median 		4.9 4.9 64.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.6
bar=donor   line=cohort median 		6.6 6.6 49.7%
14 HBA1 protein_coding 1.2
bar=donor   line=cohort median 		2.6 2.6 33.9%
15 HBA2 protein_coding 3.9
bar=donor   line=cohort median 		5.6 5.6 31.2%
◂ Previous Donor Back to Donor List Next Donor ▸