GSM5528689

Dataset: gse182409 • Sample: T193 • Status: Pregnancy-stage cohort
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Quality Control Metrics

52,543,200 Total counts Group median: 70,855,220 • 10.6%ile (↓ Low)
32,745 Detected genes Group median: 31,576 • 78.4%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 68.2%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

36.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.53
bar=donor   line=cohort median 		9.31 2.4%
CETP Lipid Metabolism 0.46
bar=donor   line=cohort median 		1.18 10.7%
SIRT6 Sirtuin Family 2.24
bar=donor   line=cohort median 		2.22 54.1%
SIRT1 Sirtuin Family 5.50
bar=donor   line=cohort median 		5.50 47.2%
SIRT3 Sirtuin Family 2.03
bar=donor   line=cohort median 		2.33 11.4%
IGF1R Insulin/IGF-1 Signaling 6.48
bar=donor   line=cohort median 		7.09 7.2%
KLOTHO Anti-aging 1.15
bar=donor   line=cohort median 		0.66 81.0%
IRS2 Insulin/IGF-1 Signaling 5.69
bar=donor   line=cohort median 		5.59 59.0%
TP53 Tumor Suppression 3.13
bar=donor   line=cohort median 		2.72 75.5%
SHC1 Signal Transduction 3.73
bar=donor   line=cohort median 		3.95 14.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.4 956,905
2 ENSG00000258486 ENSG00000258486 13.8 1,622,071
3 ENSG00000265150 ENSG00000265150 13.8 1,869,579
4 B2M ENSG00000166710 protein_coding 13.5 467,788
5 MALAT1 ENSG00000251562 lncRNA 13.2 652,393
6 AL355075.4 ENSG00000259001 lncRNA 12.9 433,138
7 EEF1A1 ENSG00000156508 protein_coding 12.8 295,661
8 S100A9 ENSG00000163220 protein_coding 12.4 369,712
9 ALAS2 ENSG00000158578 protein_coding 12.3 412,403
10 RMRP ENSG00000269900 lncRNA 11.9 195,255

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.2
bar=donor   line=cohort median 		11.8 11.8 11.3%
2 S100A9 protein_coding 12.4
bar=donor   line=cohort median 		13.1 13.1 7.9%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 58.6%
4 CXCL8 protein_coding 6.7
bar=donor   line=cohort median 		7.6 7.6 22.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.2
bar=donor   line=cohort median 		4.0 4.0 26.4%
6 FCGR3B protein_coding 11.0
bar=donor   line=cohort median 		11.3 11.3 27.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 44.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 6.6
bar=donor   line=cohort median 		5.3 5.3 99.7%
9 CD3E protein_coding 3.0
bar=donor   line=cohort median 		2.6 2.6 66.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median 		6.3 6.3 83.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.5
bar=donor   line=cohort median 		3.4 3.4 89.4%
12 GNLY protein_coding 5.2
bar=donor   line=cohort median 		4.9 4.9 66.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.8
bar=donor   line=cohort median 		6.6 6.6 65.4%
14 HBA1 protein_coding 6.3
bar=donor   line=cohort median 		2.6 2.6 86.6%
15 HBA2 protein_coding 9.1
bar=donor   line=cohort median 		5.6 5.6 85.3%
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