GSM5528690

Dataset: gse182409 • Sample: T194 • Status: Pregnancy-stage cohort
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Quality Control Metrics

59,345,799 Total counts Group median: 70,855,220 • 22.9%ile (↓ Low)
27,726 Detected genes Group median: 31,576 • 13.4%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 44.9%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

36.4Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.43
bar=donor   line=cohort median 		9.31 0.3%
CETP Lipid Metabolism 1.63
bar=donor   line=cohort median 		1.18 76.2%
SIRT6 Sirtuin Family 2.36
bar=donor   line=cohort median 		2.22 70.7%
SIRT1 Sirtuin Family 5.41
bar=donor   line=cohort median 		5.50 25.9%
SIRT3 Sirtuin Family 2.14
bar=donor   line=cohort median 		2.33 22.4%
IGF1R Insulin/IGF-1 Signaling 6.44
bar=donor   line=cohort median 		7.09 5.9%
KLOTHO Anti-aging 0.90
bar=donor   line=cohort median 		0.66 66.6%
IRS2 Insulin/IGF-1 Signaling 4.72
bar=donor   line=cohort median 		5.59 4.5%
TP53 Tumor Suppression 3.31
bar=donor   line=cohort median 		2.72 85.2%
SHC1 Signal Transduction 3.62
bar=donor   line=cohort median 		3.95 6.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 14.5 796,297
2 ENSG00000265150 ENSG00000265150 14.5 789,468
3 7SK ENSG00000202198 misc_RNA 14.0 1,268,353
4 ALAS2 ENSG00000158578 protein_coding 13.6 278,298
5 B2M ENSG00000166710 protein_coding 13.0 635,867
6 MALAT1 ENSG00000251562 lncRNA 13.0 535,268
7 AL355075.4 ENSG00000259001 lncRNA 13.0 428,007
8 EPB41 ENSG00000159023 protein_coding 12.8 163,077
9 SLC25A37 ENSG00000147454 protein_coding 12.8 169,519
10 ADIPOR1 ENSG00000159346 protein_coding 12.5 146,511

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 10.8
bar=donor   line=cohort median 		11.8 11.8 2.4%
2 S100A9 protein_coding 12.0
bar=donor   line=cohort median 		13.1 13.1 1.7%
3 IL1B protein_coding 5.7
bar=donor   line=cohort median 		6.9 6.9 3.8%
4 CXCL8 protein_coding 4.6
bar=donor   line=cohort median 		7.6 7.6 0.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.0
bar=donor   line=cohort median 		4.0 4.0 5.1%
6 FCGR3B protein_coding 11.0
bar=donor   line=cohort median 		11.3 11.3 27.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.4
bar=donor   line=cohort median 		10.9 10.9 18.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 6.1
bar=donor   line=cohort median 		5.3 5.3 98.3%
9 CD3E protein_coding 3.4
bar=donor   line=cohort median 		2.6 2.6 85.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median 		6.3 6.3 83.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.5
bar=donor   line=cohort median 		3.4 3.4 90.1%
12 GNLY protein_coding 5.2
bar=donor   line=cohort median 		4.9 4.9 71.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.8
bar=donor   line=cohort median 		6.6 6.6 32.5%
14 HBA1 protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 54.5%
15 HBA2 protein_coding 6.0
bar=donor   line=cohort median 		5.6 5.6 53.8%
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