GSM5528691

Dataset: gse182409 • Sample: T195 • Status: Pregnancy-stage cohort
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Quality Control Metrics

65,041,625 Total counts Group median: 70,855,220 • 33.9%ile (≈ Median)
26,333 Detected genes Group median: 31,576 • 3.1%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 88.0%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

41.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.40
bar=donor   line=cohort median 		9.31 54.8%
CETP Lipid Metabolism 2.03
bar=donor   line=cohort median 		1.18 90.7%
SIRT6 Sirtuin Family 2.44
bar=donor   line=cohort median 		2.22 80.3%
SIRT1 Sirtuin Family 5.30
bar=donor   line=cohort median 		5.50 7.9%
SIRT3 Sirtuin Family 2.22
bar=donor   line=cohort median 		2.33 30.7%
IGF1R Insulin/IGF-1 Signaling 6.50
bar=donor   line=cohort median 		7.09 8.6%
KLOTHO Anti-aging -0.19
bar=donor   line=cohort median 		0.66 3.8%
IRS2 Insulin/IGF-1 Signaling 4.75
bar=donor   line=cohort median 		5.59 5.9%
TP53 Tumor Suppression 3.38
bar=donor   line=cohort median 		2.72 88.6%
SHC1 Signal Transduction 3.88
bar=donor   line=cohort median 		3.95 43.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.4 1,514,576
2 ENSG00000258486 ENSG00000258486 14.3 1,539,946
3 MALAT1 ENSG00000251562 lncRNA 13.8 551,856
4 7SK ENSG00000202198 misc_RNA 13.7 1,061,460
5 ALAS2 ENSG00000158578 protein_coding 13.3 840,501
6 TENT5C ENSG00000183508 protein_coding 12.7 295,261
7 SLC25A37 ENSG00000147454 protein_coding 12.6 466,830
8 EPB41 ENSG00000159023 protein_coding 12.5 474,605
9 AL355075.4 ENSG00000259001 lncRNA 12.5 551,657
10 B2M ENSG00000166710 protein_coding 12.5 553,856

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 10.6
bar=donor   line=cohort median 		11.8 11.8 1.0%
2 S100A9 protein_coding 12.0
bar=donor   line=cohort median 		13.1 13.1 1.0%
3 IL1B protein_coding 6.1
bar=donor   line=cohort median 		6.9 6.9 13.4%
4 CXCL8 protein_coding 8.1
bar=donor   line=cohort median 		7.6 7.6 70.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.7
bar=donor   line=cohort median 		4.0 4.0 18.2%
6 FCGR3B protein_coding 9.6
bar=donor   line=cohort median 		11.3 11.3 1.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.4
bar=donor   line=cohort median 		10.9 10.9 14.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 24.3%
9 CD3E protein_coding 4.9
bar=donor   line=cohort median 		2.6 2.6 99.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median 		6.3 6.3 52.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 6.2
bar=donor   line=cohort median 		3.4 3.4 99.7%
12 GNLY protein_coding 6.3
bar=donor   line=cohort median 		4.9 4.9 99.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 12.3
bar=donor   line=cohort median 		6.6 6.6 94.2%
14 HBA1 protein_coding 6.5
bar=donor   line=cohort median 		2.6 2.6 87.3%
15 HBA2 protein_coding 10.0
bar=donor   line=cohort median 		5.6 5.6 89.4%
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