GSM5528694

Dataset: gse182409 • Sample: T198 • Status: Pregnancy-stage cohort
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Quality Control Metrics

82,685,563 Total counts Group median: 70,855,220 • 75.7%ile (↑ High)
32,279 Detected genes Group median: 31,576 • 67.5%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 70.9%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

70.8Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.83
bar=donor   line=cohort median 		9.31 85.2%
CETP Lipid Metabolism 0.94
bar=donor   line=cohort median 		1.18 33.5%
SIRT6 Sirtuin Family 2.74
bar=donor   line=cohort median 		2.22 96.9%
SIRT1 Sirtuin Family 5.44
bar=donor   line=cohort median 		5.50 33.5%
SIRT3 Sirtuin Family 2.86
bar=donor   line=cohort median 		2.33 94.8%
IGF1R Insulin/IGF-1 Signaling 7.17
bar=donor   line=cohort median 		7.09 59.0%
KLOTHO Anti-aging -0.12
bar=donor   line=cohort median 		0.66 6.6%
IRS2 Insulin/IGF-1 Signaling 6.86
bar=donor   line=cohort median 		5.59 99.0%
TP53 Tumor Suppression 4.39
bar=donor   line=cohort median 		2.72 99.7%
SHC1 Signal Transduction 4.63
bar=donor   line=cohort median 		3.95 99.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.3 3,580,341
2 ENSG00000258486 ENSG00000258486 15.2 3,136,283
3 7SK ENSG00000202198 misc_RNA 14.7 1,709,623
4 MALAT1 ENSG00000251562 lncRNA 13.8 600,315
5 S100A9 ENSG00000163220 protein_coding 13.4 559,403
6 AL355075.4 ENSG00000259001 lncRNA 13.1 642,106
7 B2M ENSG00000166710 protein_coding 13.1 682,607
8 NAMPT ENSG00000105835 protein_coding 12.6 343,154
9 NEAT1 ENSG00000245532 lncRNA 12.6 104,397
10 SORL1 ENSG00000137642 protein_coding 12.4 242,018

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 81.8%
2 S100A9 protein_coding 13.4
bar=donor   line=cohort median 		13.1 13.1 79.8%
3 IL1B protein_coding 6.6
bar=donor   line=cohort median 		6.9 6.9 33.2%
4 CXCL8 protein_coding 7.2
bar=donor   line=cohort median 		7.6 7.6 39.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.0
bar=donor   line=cohort median 		4.0 4.0 22.9%
6 FCGR3B protein_coding 11.9
bar=donor   line=cohort median 		11.3 11.3 88.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 39.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 39.4%
9 CD3E protein_coding 2.3
bar=donor   line=cohort median 		2.6 2.6 33.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.5
bar=donor   line=cohort median 		6.3 6.3 67.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.1
bar=donor   line=cohort median 		3.4 3.4 1.7%
12 GNLY protein_coding 4.0
bar=donor   line=cohort median 		4.9 4.9 7.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.3
bar=donor   line=cohort median 		6.6 6.6 3.1%
14 HBA1 protein_coding -1.5
bar=donor   line=cohort median 		2.6 2.6 1.7%
15 HBA2 protein_coding 2.0
bar=donor   line=cohort median 		5.6 5.6 2.4%
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