GSM5528695

Dataset: gse182409 • Sample: T199 • Status: Pregnancy-stage cohort
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Quality Control Metrics

66,831,999 Total counts Group median: 70,855,220 • 38.7%ile (≈ Median)
33,016 Detected genes Group median: 31,576 • 81.2%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 61.3%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

53.2Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.80
bar=donor   line=cohort median 		9.31 13.5%
CETP Lipid Metabolism 0.87
bar=donor   line=cohort median 		1.18 26.6%
SIRT6 Sirtuin Family 1.93
bar=donor   line=cohort median 		2.22 16.9%
SIRT1 Sirtuin Family 5.64
bar=donor   line=cohort median 		5.50 76.9%
SIRT3 Sirtuin Family 2.25
bar=donor   line=cohort median 		2.33 37.6%
IGF1R Insulin/IGF-1 Signaling 7.60
bar=donor   line=cohort median 		7.09 92.8%
KLOTHO Anti-aging 1.93
bar=donor   line=cohort median 		0.66 99.7%
IRS2 Insulin/IGF-1 Signaling 6.18
bar=donor   line=cohort median 		5.59 92.1%
TP53 Tumor Suppression 2.54
bar=donor   line=cohort median 		2.72 41.7%
SHC1 Signal Transduction 3.85
bar=donor   line=cohort median 		3.95 34.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.6 2,551,968
2 ENSG00000258486 ENSG00000258486 14.5 2,388,598
3 7SK ENSG00000202198 misc_RNA 14.3 1,624,197
4 MALAT1 ENSG00000251562 lncRNA 13.7 872,117
5 B2M ENSG00000166710 protein_coding 13.0 553,100
6 S100A9 ENSG00000163220 protein_coding 12.9 669,615
7 NAMPT ENSG00000105835 protein_coding 12.7 383,314
8 AL355075.4 ENSG00000259001 lncRNA 12.6 564,678
9 BNIP3L ENSG00000104765 protein_coding 12.6 302,793
10 SORL1 ENSG00000137642 protein_coding 12.3 329,424

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.5
bar=donor   line=cohort median 		11.8 11.8 29.8%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median 		13.1 13.1 37.3%
3 IL1B protein_coding 7.3
bar=donor   line=cohort median 		6.9 6.9 82.5%
4 CXCL8 protein_coding 9.0
bar=donor   line=cohort median 		7.6 7.6 93.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.6
bar=donor   line=cohort median 		4.0 4.0 14.7%
6 FCGR3B protein_coding 11.2
bar=donor   line=cohort median 		11.3 11.3 36.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 9.8
bar=donor   line=cohort median 		10.9 10.9 3.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.6
bar=donor   line=cohort median 		5.3 5.3 3.1%
9 CD3E protein_coding 3.2
bar=donor   line=cohort median 		2.6 2.6 82.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.8
bar=donor   line=cohort median 		6.3 6.3 18.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.1
bar=donor   line=cohort median 		3.4 3.4 81.8%
12 GNLY protein_coding 5.3
bar=donor   line=cohort median 		4.9 4.9 78.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.8
bar=donor   line=cohort median 		6.6 6.6 30.5%
14 HBA1 protein_coding -0.1
bar=donor   line=cohort median 		2.6 2.6 20.2%
15 HBA2 protein_coding 2.7
bar=donor   line=cohort median 		5.6 5.6 11.3%
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