GSM5528696

Dataset: gse182409 • Sample: T200 • Status: Pregnancy-stage cohort
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Quality Control Metrics

64,159,824 Total counts Group median: 70,855,220 • 30.5%ile (≈ Median)
33,176 Detected genes Group median: 31,576 • 84.6%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 46.2%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

54.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.16
bar=donor   line=cohort median 		9.31 39.0%
CETP Lipid Metabolism 0.81
bar=donor   line=cohort median 		1.18 21.7%
SIRT6 Sirtuin Family 2.05
bar=donor   line=cohort median 		2.22 27.2%
SIRT1 Sirtuin Family 5.40
bar=donor   line=cohort median 		5.50 23.1%
SIRT3 Sirtuin Family 3.09
bar=donor   line=cohort median 		2.33 99.7%
IGF1R Insulin/IGF-1 Signaling 7.36
bar=donor   line=cohort median 		7.09 79.0%
KLOTHO Anti-aging -0.14
bar=donor   line=cohort median 		0.66 5.2%
IRS2 Insulin/IGF-1 Signaling 6.15
bar=donor   line=cohort median 		5.59 91.4%
TP53 Tumor Suppression 3.21
bar=donor   line=cohort median 		2.72 79.0%
SHC1 Signal Transduction 4.14
bar=donor   line=cohort median 		3.95 74.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.7 1,523,725
2 ENSG00000258486 ENSG00000258486 14.6 1,345,007
3 7SK ENSG00000202198 misc_RNA 14.0 1,190,088
4 MALAT1 ENSG00000251562 lncRNA 13.4 773,178
5 ALAS2 ENSG00000158578 protein_coding 13.0 241,282
6 B2M ENSG00000166710 protein_coding 12.7 491,504
7 EEF1A1 ENSG00000156508 protein_coding 12.5 211,990
8 S100A9 ENSG00000163220 protein_coding 12.5 459,462
9 AL355075.4 ENSG00000259001 lncRNA 12.2 372,071
10 SLC25A37 ENSG00000147454 protein_coding 12.1 296,790

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.1
bar=donor   line=cohort median 		11.8 11.8 7.9%
2 S100A9 protein_coding 12.5
bar=donor   line=cohort median 		13.1 13.1 11.3%
3 IL1B protein_coding 5.8
bar=donor   line=cohort median 		6.9 6.9 5.8%
4 CXCL8 protein_coding 6.4
bar=donor   line=cohort median 		7.6 7.6 16.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.7
bar=donor   line=cohort median 		4.0 4.0 43.5%
6 FCGR3B protein_coding 11.1
bar=donor   line=cohort median 		11.3 11.3 35.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 72.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 72.9%
9 CD3E protein_coding 3.8
bar=donor   line=cohort median 		2.6 2.6 95.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.6
bar=donor   line=cohort median 		6.3 6.3 70.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.6
bar=donor   line=cohort median 		3.4 3.4 57.9%
12 GNLY protein_coding 4.2
bar=donor   line=cohort median 		4.9 4.9 13.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.3
bar=donor   line=cohort median 		6.6 6.6 81.8%
14 HBA1 protein_coding 4.8
bar=donor   line=cohort median 		2.6 2.6 74.3%
15 HBA2 protein_coding 7.7
bar=donor   line=cohort median 		5.6 5.6 70.2%
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