GSM5528698

Dataset: gse182409 • Sample: T202 • Status: Pregnancy-stage cohort
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Quality Control Metrics

32,225,132 Total counts Group median: 70,855,220 • 1.0%ile (↓ Low)
32,031 Detected genes Group median: 31,576 • 58.6%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 99.7%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

48.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.84
bar=donor   line=cohort median 		9.31 16.2%
CETP Lipid Metabolism 1.53
bar=donor   line=cohort median 		1.18 71.4%
SIRT6 Sirtuin Family 2.08
bar=donor   line=cohort median 		2.22 32.8%
SIRT1 Sirtuin Family 5.49
bar=donor   line=cohort median 		5.50 46.6%
SIRT3 Sirtuin Family 2.48
bar=donor   line=cohort median 		2.33 72.8%
IGF1R Insulin/IGF-1 Signaling 6.91
bar=donor   line=cohort median 		7.09 32.8%
KLOTHO Anti-aging -0.07
bar=donor   line=cohort median 		0.66 10.0%
IRS2 Insulin/IGF-1 Signaling 5.66
bar=donor   line=cohort median 		5.59 56.2%
TP53 Tumor Suppression 3.37
bar=donor   line=cohort median 		2.72 87.2%
SHC1 Signal Transduction 4.01
bar=donor   line=cohort median 		3.95 59.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 15.2 541,882
2 ENSG00000258486 ENSG00000258486 14.8 672,673
3 ENSG00000265150 ENSG00000265150 14.1 813,781
4 ALAS2 ENSG00000158578 protein_coding 13.5 123,234
5 B2M ENSG00000166710 protein_coding 13.4 248,494
6 MALAT1 ENSG00000251562 lncRNA 13.4 461,313
7 S100A9 ENSG00000163220 protein_coding 12.9 191,384
8 UBB ENSG00000170315 protein_coding 12.6 58,931
9 NEAT1 ENSG00000245532 lncRNA 12.6 66,315
10 EEF1A1 ENSG00000156508 protein_coding 12.5 115,895

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.2
bar=donor   line=cohort median 		11.8 11.8 9.2%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median 		13.1 13.1 36.6%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 52.4%
4 CXCL8 protein_coding 4.8
bar=donor   line=cohort median 		7.6 7.6 1.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.8
bar=donor   line=cohort median 		4.0 4.0 20.9%
6 FCGR3B protein_coding 11.8
bar=donor   line=cohort median 		11.3 11.3 79.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.6
bar=donor   line=cohort median 		10.9 10.9 96.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 6.0
bar=donor   line=cohort median 		5.3 5.3 95.5%
9 CD3E protein_coding 3.3
bar=donor   line=cohort median 		2.6 2.6 83.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.0
bar=donor   line=cohort median 		6.3 6.3 1.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median 		3.4 3.4 64.0%
12 GNLY protein_coding 3.8
bar=donor   line=cohort median 		4.9 4.9 4.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.9
bar=donor   line=cohort median 		6.6 6.6 36.0%
14 HBA1 protein_coding 0.5
bar=donor   line=cohort median 		2.6 2.6 27.7%
15 HBA2 protein_coding 3.2
bar=donor   line=cohort median 		5.6 5.6 21.6%
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