GSM5528699

Dataset: gse182409 • Sample: T203 • Status: Pregnancy-stage cohort
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Quality Control Metrics

64,091,641 Total counts Group median: 70,855,220 • 29.8%ile (≈ Median)
31,431 Detected genes Group median: 31,576 • 46.2%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 93.5%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

43.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.50
bar=donor   line=cohort median 		9.31 1.0%
CETP Lipid Metabolism 1.38
bar=donor   line=cohort median 		1.18 65.9%
SIRT6 Sirtuin Family 2.27
bar=donor   line=cohort median 		2.22 59.7%
SIRT1 Sirtuin Family 5.20
bar=donor   line=cohort median 		5.50 3.1%
SIRT3 Sirtuin Family 2.18
bar=donor   line=cohort median 		2.33 26.6%
IGF1R Insulin/IGF-1 Signaling 7.62
bar=donor   line=cohort median 		7.09 94.8%
KLOTHO Anti-aging 0.58
bar=donor   line=cohort median 		0.66 42.4%
IRS2 Insulin/IGF-1 Signaling 5.18
bar=donor   line=cohort median 		5.59 19.0%
TP53 Tumor Suppression 3.57
bar=donor   line=cohort median 		2.72 92.1%
SHC1 Signal Transduction 3.80
bar=donor   line=cohort median 		3.95 25.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 16.1 1,126,143
2 ENSG00000258486 ENSG00000258486 15.9 1,831,318
3 ALAS2 ENSG00000158578 protein_coding 14.6 715,131
4 EPB41 ENSG00000159023 protein_coding 14.0 163,579
5 BNIP3L ENSG00000104765 protein_coding 13.9 205,245
6 SLC25A37 ENSG00000147454 protein_coding 13.8 281,586
7 TENT5C ENSG00000183508 protein_coding 13.8 157,092
8 7SK ENSG00000202198 misc_RNA 13.7 2,321,606
9 ENSG00000138293 ENSG00000138293 13.6 171,343
10 MALAT1 ENSG00000251562 lncRNA 13.4 667,201

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.2
bar=donor   line=cohort median 		11.8 11.8 10.6%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 25.7%
3 IL1B protein_coding 6.8
bar=donor   line=cohort median 		6.9 6.9 45.5%
4 CXCL8 protein_coding 7.9
bar=donor   line=cohort median 		7.6 7.6 64.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.5
bar=donor   line=cohort median 		4.0 4.0 10.6%
6 FCGR3B protein_coding 11.1
bar=donor   line=cohort median 		11.3 11.3 29.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.2
bar=donor   line=cohort median 		10.9 10.9 11.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.6
bar=donor   line=cohort median 		5.3 5.3 4.5%
9 CD3E protein_coding 2.2
bar=donor   line=cohort median 		2.6 2.6 31.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.1
bar=donor   line=cohort median 		6.3 6.3 36.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.9
bar=donor   line=cohort median 		3.4 3.4 23.6%
12 GNLY protein_coding 4.3
bar=donor   line=cohort median 		4.9 4.9 22.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.3
bar=donor   line=cohort median 		6.6 6.6 17.5%
14 HBA1 protein_coding -0.3
bar=donor   line=cohort median 		2.6 2.6 16.8%
15 HBA2 protein_coding 3.5
bar=donor   line=cohort median 		5.6 5.6 26.4%
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