GSM5528702

Dataset: gse182409 • Sample: T206 • Status: Pregnancy-stage cohort
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Quality Control Metrics

65,246,654 Total counts Group median: 70,855,220 • 34.6%ile (≈ Median)
30,897 Detected genes Group median: 31,576 • 41.4%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 98.3%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

52.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.73
bar=donor   line=cohort median 		9.31 81.7%
CETP Lipid Metabolism 1.20
bar=donor   line=cohort median 		1.18 52.1%
SIRT6 Sirtuin Family 2.42
bar=donor   line=cohort median 		2.22 79.0%
SIRT1 Sirtuin Family 5.37
bar=donor   line=cohort median 		5.50 19.7%
SIRT3 Sirtuin Family 2.26
bar=donor   line=cohort median 		2.33 42.4%
IGF1R Insulin/IGF-1 Signaling 6.87
bar=donor   line=cohort median 		7.09 27.9%
KLOTHO Anti-aging 1.17
bar=donor   line=cohort median 		0.66 81.7%
IRS2 Insulin/IGF-1 Signaling 5.37
bar=donor   line=cohort median 		5.59 30.7%
TP53 Tumor Suppression 2.72
bar=donor   line=cohort median 		2.72 49.3%
SHC1 Signal Transduction 4.02
bar=donor   line=cohort median 		3.95 61.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.3 557,985
2 ENSG00000258486 ENSG00000258486 15.0 558,004
3 7SK ENSG00000202198 misc_RNA 14.2 1,083,471
4 MALAT1 ENSG00000251562 lncRNA 13.7 604,442
5 AL355075.4 ENSG00000259001 lncRNA 12.9 390,700
6 B2M ENSG00000166710 protein_coding 12.7 490,708
7 SLC25A37 ENSG00000147454 protein_coding 12.7 355,157
8 EPB41 ENSG00000159023 protein_coding 12.4 337,155
9 S100A9 ENSG00000163220 protein_coding 12.3 412,178
10 BNIP3L ENSG00000104765 protein_coding 12.2 413,063

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.0
bar=donor   line=cohort median 		11.8 11.8 5.8%
2 S100A9 protein_coding 12.3
bar=donor   line=cohort median 		13.1 13.1 5.1%
3 IL1B protein_coding 6.7
bar=donor   line=cohort median 		6.9 6.9 40.8%
4 CXCL8 protein_coding 6.8
bar=donor   line=cohort median 		7.6 7.6 29.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.4
bar=donor   line=cohort median 		4.0 4.0 31.8%
6 FCGR3B protein_coding 9.9
bar=donor   line=cohort median 		11.3 11.3 2.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.0
bar=donor   line=cohort median 		10.9 10.9 6.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 27.1%
9 CD3E protein_coding 3.9
bar=donor   line=cohort median 		2.6 2.6 96.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.0
bar=donor   line=cohort median 		6.3 6.3 33.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.1
bar=donor   line=cohort median 		3.4 3.4 81.2%
12 GNLY protein_coding 6.1
bar=donor   line=cohort median 		4.9 4.9 94.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.5
bar=donor   line=cohort median 		6.6 6.6 46.9%
14 HBA1 protein_coding 1.2
bar=donor   line=cohort median 		2.6 2.6 33.2%
15 HBA2 protein_coding 3.7
bar=donor   line=cohort median 		5.6 5.6 27.7%
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