GSM5528704

Dataset: gse182409 • Sample: T208 • Status: Pregnancy-stage cohort
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Quality Control Metrics

70,817,446 Total counts Group median: 70,855,220 • 49.7%ile (≈ Median)
32,064 Detected genes Group median: 31,576 • 59.9%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 64.7%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

63.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.65
bar=donor   line=cohort median 		9.31 6.6%
CETP Lipid Metabolism 1.10
bar=donor   line=cohort median 		1.18 42.4%
SIRT6 Sirtuin Family 2.47
bar=donor   line=cohort median 		2.22 83.8%
SIRT1 Sirtuin Family 5.47
bar=donor   line=cohort median 		5.50 38.3%
SIRT3 Sirtuin Family 2.26
bar=donor   line=cohort median 		2.33 41.0%
IGF1R Insulin/IGF-1 Signaling 7.61
bar=donor   line=cohort median 		7.09 93.5%
KLOTHO Anti-aging 1.02
bar=donor   line=cohort median 		0.66 71.4%
IRS2 Insulin/IGF-1 Signaling 5.96
bar=donor   line=cohort median 		5.59 83.8%
TP53 Tumor Suppression 3.75
bar=donor   line=cohort median 		2.72 96.2%
SHC1 Signal Transduction 4.13
bar=donor   line=cohort median 		3.95 73.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.2 4,168,108
2 ENSG00000258486 ENSG00000258486 15.1 3,753,640
3 7SK ENSG00000202198 misc_RNA 14.2 1,419,330
4 MALAT1 ENSG00000251562 lncRNA 13.6 521,897
5 S100A9 ENSG00000163220 protein_coding 13.2 502,506
6 B2M ENSG00000166710 protein_coding 13.1 572,252
7 AL355075.4 ENSG00000259001 lncRNA 13.1 882,976
8 ALAS2 ENSG00000158578 protein_coding 12.9 986,641
9 EPB41 ENSG00000159023 protein_coding 12.6 374,167
10 NAMPT ENSG00000105835 protein_coding 12.5 305,078

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.0
bar=donor   line=cohort median 		11.8 11.8 64.0%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 54.5%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 56.5%
4 CXCL8 protein_coding 7.7
bar=donor   line=cohort median 		7.6 7.6 56.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 1.9
bar=donor   line=cohort median 		4.0 4.0 4.5%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 48.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 75.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 73.6%
9 CD3E protein_coding 3.2
bar=donor   line=cohort median 		2.6 2.6 83.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.8
bar=donor   line=cohort median 		6.3 6.3 80.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.1
bar=donor   line=cohort median 		3.4 3.4 34.6%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median 		4.9 4.9 51.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 11.5
bar=donor   line=cohort median 		6.6 6.6 92.1%
14 HBA1 protein_coding 6.8
bar=donor   line=cohort median 		2.6 2.6 88.7%
15 HBA2 protein_coding 9.5
bar=donor   line=cohort median 		5.6 5.6 87.3%
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