GSM5528708

Dataset: gse182409 • Sample: T212 • Status: Pregnancy-stage cohort
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Quality Control Metrics

50,645,047 Total counts Group median: 70,855,220 • 7.9%ile (↓ Low)
26,181 Detected genes Group median: 31,576 • 2.4%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 45.5%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

47.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.99
bar=donor   line=cohort median 		9.31 23.8%
CETP Lipid Metabolism 0.53
bar=donor   line=cohort median 		1.18 11.4%
SIRT6 Sirtuin Family 2.26
bar=donor   line=cohort median 		2.22 56.9%
SIRT1 Sirtuin Family 5.42
bar=donor   line=cohort median 		5.50 27.9%
SIRT3 Sirtuin Family 2.56
bar=donor   line=cohort median 		2.33 81.7%
IGF1R Insulin/IGF-1 Signaling 7.22
bar=donor   line=cohort median 		7.09 68.6%
KLOTHO Anti-aging 0.24
bar=donor   line=cohort median 		0.66 20.3%
IRS2 Insulin/IGF-1 Signaling 5.62
bar=donor   line=cohort median 		5.59 52.1%
TP53 Tumor Suppression 3.26
bar=donor   line=cohort median 		2.72 83.8%
SHC1 Signal Transduction 3.95
bar=donor   line=cohort median 		3.95 50.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.1 493,762
2 ENSG00000258486 ENSG00000258486 14.0 437,992
3 7SK ENSG00000202198 misc_RNA 13.9 750,402
4 MALAT1 ENSG00000251562 lncRNA 13.5 593,434
5 ALAS2 ENSG00000158578 protein_coding 13.3 345,520
6 S100A9 ENSG00000163220 protein_coding 13.0 277,501
7 B2M ENSG00000166710 protein_coding 13.0 449,636
8 AL355075.4 ENSG00000259001 lncRNA 12.6 285,652
9 SLC25A37 ENSG00000147454 protein_coding 12.3 216,098
10 NAMPT ENSG00000105835 protein_coding 12.2 212,268

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.6
bar=donor   line=cohort median 		11.8 11.8 32.5%
2 S100A9 protein_coding 13.0
bar=donor   line=cohort median 		13.1 13.1 44.2%
3 IL1B protein_coding 6.2
bar=donor   line=cohort median 		6.9 6.9 16.8%
4 CXCL8 protein_coding 5.5
bar=donor   line=cohort median 		7.6 7.6 6.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.7
bar=donor   line=cohort median 		4.0 4.0 92.8%
6 FCGR3B protein_coding 10.9
bar=donor   line=cohort median 		11.3 11.3 20.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 74.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.9
bar=donor   line=cohort median 		5.3 5.3 13.4%
9 CD3E protein_coding 3.0
bar=donor   line=cohort median 		2.6 2.6 66.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median 		6.3 6.3 48.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.4
bar=donor   line=cohort median 		3.4 3.4 87.3%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median 		4.9 4.9 50.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.4
bar=donor   line=cohort median 		6.6 6.6 3.8%
14 HBA1 protein_coding -1.4
bar=donor   line=cohort median 		2.6 2.6 2.4%
15 HBA2 protein_coding 1.9
bar=donor   line=cohort median 		5.6 5.6 1.7%
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