GSM5528710

Dataset: gse182409 • Sample: T214 • Status: Pregnancy-stage cohort
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Quality Control Metrics

62,865,144 Total counts Group median: 70,855,220 • 27.7%ile (≈ Median)
29,321 Detected genes Group median: 31,576 • 29.1%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 56.5%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

59.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.27
bar=donor   line=cohort median 		9.31 48.6%
CETP Lipid Metabolism 1.57
bar=donor   line=cohort median 		1.18 74.1%
SIRT6 Sirtuin Family 2.22
bar=donor   line=cohort median 		2.22 49.3%
SIRT1 Sirtuin Family 5.68
bar=donor   line=cohort median 		5.50 85.2%
SIRT3 Sirtuin Family 2.44
bar=donor   line=cohort median 		2.33 69.3%
IGF1R Insulin/IGF-1 Signaling 6.80
bar=donor   line=cohort median 		7.09 23.8%
KLOTHO Anti-aging 0.93
bar=donor   line=cohort median 		0.66 68.6%
IRS2 Insulin/IGF-1 Signaling 5.58
bar=donor   line=cohort median 		5.59 47.2%
TP53 Tumor Suppression 2.89
bar=donor   line=cohort median 		2.72 61.7%
SHC1 Signal Transduction 4.07
bar=donor   line=cohort median 		3.95 69.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.5 990,407
2 ENSG00000265150 ENSG00000265150 15.2 982,428
3 7SK ENSG00000202198 misc_RNA 14.8 982,565
4 AL355075.4 ENSG00000259001 lncRNA 13.6 319,827
5 S100A9 ENSG00000163220 protein_coding 13.3 401,334
6 MALAT1 ENSG00000251562 lncRNA 13.3 689,022
7 B2M ENSG00000166710 protein_coding 13.2 588,701
8 ALAS2 ENSG00000158578 protein_coding 13.1 669,356
9 NAMPT ENSG00000105835 protein_coding 12.3 261,773
10 TMSB4X ENSG00000205542 protein_coding 12.3 270,777

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 84.6%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 76.4%
3 IL1B protein_coding 6.3
bar=donor   line=cohort median 		6.9 6.9 20.9%
4 CXCL8 protein_coding 7.8
bar=donor   line=cohort median 		7.6 7.6 59.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.4
bar=donor   line=cohort median 		4.0 4.0 86.6%
6 FCGR3B protein_coding 11.2
bar=donor   line=cohort median 		11.3 11.3 41.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.5
bar=donor   line=cohort median 		10.9 10.9 91.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.6
bar=donor   line=cohort median 		5.3 5.3 79.1%
9 CD3E protein_coding 2.5
bar=donor   line=cohort median 		2.6 2.6 41.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.4
bar=donor   line=cohort median 		6.3 6.3 61.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.5
bar=donor   line=cohort median 		3.4 3.4 51.0%
12 GNLY protein_coding 6.1
bar=donor   line=cohort median 		4.9 4.9 96.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.1
bar=donor   line=cohort median 		6.6 6.6 39.4%
14 HBA1 protein_coding 1.4
bar=donor   line=cohort median 		2.6 2.6 35.3%
15 HBA2 protein_coding 3.5
bar=donor   line=cohort median 		5.6 5.6 25.7%
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