GSM5528712

Dataset: gse182409 • Sample: T216 • Status: Pregnancy-stage cohort
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Quality Control Metrics

57,651,037 Total counts Group median: 70,855,220 • 18.8%ile (↓ Low)
33,498 Detected genes Group median: 31,576 • 90.8%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 94.2%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

39.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.05
bar=donor   line=cohort median 		9.31 28.6%
CETP Lipid Metabolism 0.93
bar=donor   line=cohort median 		1.18 31.4%
SIRT6 Sirtuin Family 2.05
bar=donor   line=cohort median 		2.22 29.3%
SIRT1 Sirtuin Family 5.47
bar=donor   line=cohort median 		5.50 36.9%
SIRT3 Sirtuin Family 2.43
bar=donor   line=cohort median 		2.33 65.2%
IGF1R Insulin/IGF-1 Signaling 7.07
bar=donor   line=cohort median 		7.09 47.9%
KLOTHO Anti-aging 0.56
bar=donor   line=cohort median 		0.66 39.7%
IRS2 Insulin/IGF-1 Signaling 5.59
bar=donor   line=cohort median 		5.59 48.6%
TP53 Tumor Suppression 2.44
bar=donor   line=cohort median 		2.72 35.5%
SHC1 Signal Transduction 3.83
bar=donor   line=cohort median 		3.95 32.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.0 1,642,919
2 ENSG00000258486 ENSG00000258486 14.9 1,445,214
3 ALAS2 ENSG00000158578 protein_coding 14.5 288,550
4 7SK ENSG00000202198 misc_RNA 14.3 1,419,963
5 MALAT1 ENSG00000251562 lncRNA 13.5 1,033,109
6 SLC25A37 ENSG00000147454 protein_coding 13.3 229,133
7 EPB41 ENSG00000159023 protein_coding 13.3 186,439
8 AL355075.4 ENSG00000259001 lncRNA 13.2 490,759
9 TENT5C ENSG00000183508 protein_coding 13.1 137,621
10 ADIPOR1 ENSG00000159346 protein_coding 12.9 130,397

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 55.1%
2 S100A9 protein_coding 12.8
bar=donor   line=cohort median 		13.1 13.1 26.4%
3 IL1B protein_coding 6.4
bar=donor   line=cohort median 		6.9 6.9 25.7%
4 CXCL8 protein_coding 6.8
bar=donor   line=cohort median 		7.6 7.6 27.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.2
bar=donor   line=cohort median 		4.0 4.0 80.5%
6 FCGR3B protein_coding 10.5
bar=donor   line=cohort median 		11.3 11.3 7.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.3
bar=donor   line=cohort median 		10.9 10.9 13.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.0
bar=donor   line=cohort median 		5.3 5.3 18.2%
9 CD3E protein_coding 2.6
bar=donor   line=cohort median 		2.6 2.6 46.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.6
bar=donor   line=cohort median 		6.3 6.3 72.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.9
bar=donor   line=cohort median 		3.4 3.4 72.3%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median 		4.9 4.9 49.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 10.4
bar=donor   line=cohort median 		6.6 6.6 89.4%
14 HBA1 protein_coding 7.0
bar=donor   line=cohort median 		2.6 2.6 90.8%
15 HBA2 protein_coding 10.0
bar=donor   line=cohort median 		5.6 5.6 88.7%
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