GSM5528717

Dataset: gse182409 • Sample: T221 • Status: Pregnancy-stage cohort
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Quality Control Metrics

34,329,609 Total counts Group median: 70,855,220 • 1.7%ile (↓ Low)
29,895 Detected genes Group median: 31,576 • 36.0%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 25.0%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

48.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.05
bar=donor   line=cohort median 		9.31 29.3%
CETP Lipid Metabolism 2.42
bar=donor   line=cohort median 		1.18 97.6%
SIRT6 Sirtuin Family 2.30
bar=donor   line=cohort median 		2.22 63.8%
SIRT1 Sirtuin Family 5.23
bar=donor   line=cohort median 		5.50 3.8%
SIRT3 Sirtuin Family 2.37
bar=donor   line=cohort median 		2.33 55.5%
IGF1R Insulin/IGF-1 Signaling 6.67
bar=donor   line=cohort median 		7.09 14.1%
KLOTHO Anti-aging -0.11
bar=donor   line=cohort median 		0.66 7.2%
IRS2 Insulin/IGF-1 Signaling 5.20
bar=donor   line=cohort median 		5.59 21.0%
TP53 Tumor Suppression 3.93
bar=donor   line=cohort median 		2.72 97.6%
SHC1 Signal Transduction 4.28
bar=donor   line=cohort median 		3.95 92.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.3 1,088,602
2 ENSG00000258486 ENSG00000258486 14.9 961,948
3 7SK ENSG00000202198 misc_RNA 14.4 786,389
4 ALAS2 ENSG00000158578 protein_coding 14.3 267,307
5 AL355075.4 ENSG00000259001 lncRNA 13.4 334,904
6 MALAT1 ENSG00000251562 lncRNA 13.3 495,120
7 SLC25A37 ENSG00000147454 protein_coding 13.3 170,476
8 B2M ENSG00000166710 protein_coding 13.2 274,438
9 S100A9 ENSG00000163220 protein_coding 13.2 259,388
10 EPB41 ENSG00000159023 protein_coding 12.8 149,460

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.8
bar=donor   line=cohort median 		11.8 11.8 47.6%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 56.5%
3 IL1B protein_coding 6.0
bar=donor   line=cohort median 		6.9 6.9 8.6%
4 CXCL8 protein_coding 6.9
bar=donor   line=cohort median 		7.6 7.6 30.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.4
bar=donor   line=cohort median 		4.0 4.0 64.7%
6 FCGR3B protein_coding 10.3
bar=donor   line=cohort median 		11.3 11.3 4.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.4
bar=donor   line=cohort median 		10.9 10.9 14.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 66.8%
9 CD3E protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 71.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.4
bar=donor   line=cohort median 		6.3 6.3 2.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.9
bar=donor   line=cohort median 		3.4 3.4 71.6%
12 GNLY protein_coding 5.0
bar=donor   line=cohort median 		4.9 4.9 58.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.4
bar=donor   line=cohort median 		6.6 6.6 43.5%
14 HBA1 protein_coding 0.8
bar=donor   line=cohort median 		2.6 2.6 30.5%
15 HBA2 protein_coding 3.6
bar=donor   line=cohort median 		5.6 5.6 27.1%
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