GSM5528718

Dataset: gse182409 • Sample: T222 • Status: Pregnancy-stage cohort
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Quality Control Metrics

84,426,876 Total counts Group median: 70,855,220 • 81.2%ile (↑ High)
32,501 Detected genes Group median: 31,576 • 72.9%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 50.3%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

70.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.78
bar=donor   line=cohort median 		9.31 83.1%
CETP Lipid Metabolism 1.21
bar=donor   line=cohort median 		1.18 53.5%
SIRT6 Sirtuin Family 2.30
bar=donor   line=cohort median 		2.22 63.1%
SIRT1 Sirtuin Family 5.64
bar=donor   line=cohort median 		5.50 76.2%
SIRT3 Sirtuin Family 2.96
bar=donor   line=cohort median 		2.33 96.9%
IGF1R Insulin/IGF-1 Signaling 7.11
bar=donor   line=cohort median 		7.09 52.8%
KLOTHO Anti-aging 0.65
bar=donor   line=cohort median 		0.66 47.9%
IRS2 Insulin/IGF-1 Signaling 6.05
bar=donor   line=cohort median 		5.59 86.6%
TP53 Tumor Suppression 2.88
bar=donor   line=cohort median 		2.72 61.0%
SHC1 Signal Transduction 4.18
bar=donor   line=cohort median 		3.95 79.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.3 2,920,155
2 ENSG00000258486 ENSG00000258486 15.0 2,251,473
3 7SK ENSG00000202198 misc_RNA 14.6 1,628,873
4 B2M ENSG00000166710 protein_coding 13.7 709,270
5 ALAS2 ENSG00000158578 protein_coding 13.7 1,440,356
6 MALAT1 ENSG00000251562 lncRNA 13.4 764,447
7 AL355075.4 ENSG00000259001 lncRNA 13.3 779,734
8 BNIP3L ENSG00000104765 protein_coding 13.2 415,704
9 S100A9 ENSG00000163220 protein_coding 13.2 676,099
10 EPB41 ENSG00000159023 protein_coding 12.9 529,261

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median 		11.8 11.8 69.5%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 55.8%
3 IL1B protein_coding 7.8
bar=donor   line=cohort median 		6.9 6.9 96.9%
4 CXCL8 protein_coding 5.8
bar=donor   line=cohort median 		7.6 7.6 9.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 1.0
bar=donor   line=cohort median 		4.0 4.0 0.3%
6 FCGR3B protein_coding 12.1
bar=donor   line=cohort median 		11.3 11.3 95.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.6
bar=donor   line=cohort median 		10.9 10.9 29.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 50.3%
9 CD3E protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 65.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.5
bar=donor   line=cohort median 		6.3 6.3 64.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.3
bar=donor   line=cohort median 		3.4 3.4 42.1%
12 GNLY protein_coding 4.1
bar=donor   line=cohort median 		4.9 4.9 12.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.9
bar=donor   line=cohort median 		6.6 6.6 55.1%
14 HBA1 protein_coding 4.2
bar=donor   line=cohort median 		2.6 2.6 67.5%
15 HBA2 protein_coding 7.0
bar=donor   line=cohort median 		5.6 5.6 64.7%
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