GSM5528720

Dataset: gse182409 • Sample: T224 • Status: Pregnancy-stage cohort
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Quality Control Metrics

84,256,351 Total counts Group median: 70,855,220 • 80.5%ile (↑ High)
35,079 Detected genes Group median: 31,576 • 99.7%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 33.9%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

53.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.63
bar=donor   line=cohort median 		9.31 76.2%
CETP Lipid Metabolism 2.25
bar=donor   line=cohort median 		1.18 95.5%
SIRT6 Sirtuin Family 2.29
bar=donor   line=cohort median 		2.22 61.7%
SIRT1 Sirtuin Family 5.28
bar=donor   line=cohort median 		5.50 6.6%
SIRT3 Sirtuin Family 2.50
bar=donor   line=cohort median 		2.33 74.8%
IGF1R Insulin/IGF-1 Signaling 6.91
bar=donor   line=cohort median 		7.09 33.5%
KLOTHO Anti-aging 0.53
bar=donor   line=cohort median 		0.66 34.1%
IRS2 Insulin/IGF-1 Signaling 4.74
bar=donor   line=cohort median 		5.59 5.2%
TP53 Tumor Suppression 2.97
bar=donor   line=cohort median 		2.72 67.2%
SHC1 Signal Transduction 4.20
bar=donor   line=cohort median 		3.95 81.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.1 1,048,219
2 ENSG00000265150 ENSG00000265150 14.0 1,425,859
3 ENSG00000258486 ENSG00000258486 13.9 1,416,548
4 MALAT1 ENSG00000251562 lncRNA 13.6 1,336,327
5 B2M ENSG00000166710 protein_coding 13.0 1,066,623
6 AL355075.4 ENSG00000259001 lncRNA 12.8 505,062
7 ALAS2 ENSG00000158578 protein_coding 12.6 345,000
8 SLC25A37 ENSG00000147454 protein_coding 12.5 302,352
9 EPB41 ENSG00000159023 protein_coding 12.4 180,393
10 BNIP3L ENSG00000104765 protein_coding 12.4 224,195

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.2
bar=donor   line=cohort median 		11.8 11.8 9.9%
2 S100A9 protein_coding 12.3
bar=donor   line=cohort median 		13.1 13.1 4.5%
3 IL1B protein_coding 6.6
bar=donor   line=cohort median 		6.9 6.9 36.6%
4 CXCL8 protein_coding 7.0
bar=donor   line=cohort median 		7.6 7.6 33.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 1.3
bar=donor   line=cohort median 		4.0 4.0 1.7%
6 FCGR3B protein_coding 11.1
bar=donor   line=cohort median 		11.3 11.3 29.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.0
bar=donor   line=cohort median 		10.9 10.9 5.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.7
bar=donor   line=cohort median 		5.3 5.3 83.9%
9 CD3E protein_coding 3.7
bar=donor   line=cohort median 		2.6 2.6 92.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.9
bar=donor   line=cohort median 		6.3 6.3 23.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.6
bar=donor   line=cohort median 		3.4 3.4 94.2%
12 GNLY protein_coding 5.4
bar=donor   line=cohort median 		4.9 4.9 80.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.2
bar=donor   line=cohort median 		6.6 6.6 72.3%
14 HBA1 protein_coding 6.3
bar=donor   line=cohort median 		2.6 2.6 86.0%
15 HBA2 protein_coding 8.7
bar=donor   line=cohort median 		5.6 5.6 83.2%
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