GSM5528721

Dataset: gse182409 • Sample: T225 • Status: Pregnancy-stage cohort

Quality Control Metrics

45,306,689 Total counts Group median: 70,855,220 • 4.5%ile (↓ Low)
26,948 Detected genes Group median: 31,576 • 5.8%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 46.9%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

63.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.38
bar=donor   line=cohort median
9.31 53.5%
CETP Lipid Metabolism 1.63
bar=donor   line=cohort median
1.18 76.9%
SIRT6 Sirtuin Family 2.12
bar=donor   line=cohort median
2.22 38.3%
SIRT1 Sirtuin Family 5.60
bar=donor   line=cohort median
5.50 67.9%
SIRT3 Sirtuin Family 2.69
bar=donor   line=cohort median
2.33 88.6%
IGF1R Insulin/IGF-1 Signaling 7.43
bar=donor   line=cohort median
7.09 85.9%
KLOTHO Anti-aging -0.06
bar=donor   line=cohort median
0.66 10.7%
IRS2 Insulin/IGF-1 Signaling 5.57
bar=donor   line=cohort median
5.59 44.5%
TP53 Tumor Suppression 3.32
bar=donor   line=cohort median
2.72 85.9%
SHC1 Signal Transduction 4.20
bar=donor   line=cohort median
3.95 82.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.3 696,791
2 MALAT1 ENSG00000251562 lncRNA 13.6 469,758
3 ENSG00000258486 ENSG00000258486 13.4 575,177
4 ENSG00000265150 ENSG00000265150 13.2 630,830
5 B2M ENSG00000166710 protein_coding 12.9 311,463
6 S100A9 ENSG00000163220 protein_coding 12.7 192,501
7 AL355075.4 ENSG00000259001 lncRNA 12.7 268,938
8 ALAS2 ENSG00000158578 protein_coding 12.6 233,722
9 BNIP3L ENSG00000104765 protein_coding 12.4 207,644
10 EPB41 ENSG00000159023 protein_coding 12.3 213,389

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.5
bar=donor   line=cohort median
11.8 11.8 26.4%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median
13.1 13.1 22.3%
3 IL1B protein_coding 6.7
bar=donor   line=cohort median
6.9 6.9 44.2%
4 CXCL8 protein_coding 8.2
bar=donor   line=cohort median
7.6 7.6 72.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 1.7
bar=donor   line=cohort median
4.0 4.0 2.4%
6 FCGR3B protein_coding 10.9
bar=donor   line=cohort median
11.3 11.3 18.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.7
bar=donor   line=cohort median
10.9 10.9 36.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median
5.3 5.3 46.2%
9 CD3E protein_coding 3.2
bar=donor   line=cohort median
2.6 2.6 79.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median
6.3 6.3 87.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.6
bar=donor   line=cohort median
3.4 3.4 55.8%
12 GNLY protein_coding 4.7
bar=donor   line=cohort median
4.9 4.9 38.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.8
bar=donor   line=cohort median
6.6 6.6 87.3%
14 HBA1 protein_coding 4.7
bar=donor   line=cohort median
2.6 2.6 72.9%
15 HBA2 protein_coding 7.3
bar=donor   line=cohort median
5.6 5.6 68.2%