GSM5528725

Dataset: gse182409 • Sample: T229 • Status: Pregnancy-stage cohort
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Quality Control Metrics

68,152,448 Total counts Group median: 70,855,220 • 42.8%ile (≈ Median)
32,711 Detected genes Group median: 31,576 • 77.7%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 18.2%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

60.4Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.49
bar=donor   line=cohort median 		9.31 65.9%
CETP Lipid Metabolism 1.35
bar=donor   line=cohort median 		1.18 63.1%
SIRT6 Sirtuin Family 2.19
bar=donor   line=cohort median 		2.22 47.2%
SIRT1 Sirtuin Family 5.41
bar=donor   line=cohort median 		5.50 26.6%
SIRT3 Sirtuin Family 2.38
bar=donor   line=cohort median 		2.33 57.6%
IGF1R Insulin/IGF-1 Signaling 7.46
bar=donor   line=cohort median 		7.09 87.9%
KLOTHO Anti-aging 0.09
bar=donor   line=cohort median 		0.66 16.9%
IRS2 Insulin/IGF-1 Signaling 5.80
bar=donor   line=cohort median 		5.59 67.2%
TP53 Tumor Suppression 3.21
bar=donor   line=cohort median 		2.72 81.0%
SHC1 Signal Transduction 4.26
bar=donor   line=cohort median 		3.95 90.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.7 2,932,220
2 ENSG00000265150 ENSG00000265150 15.4 3,245,574
3 7SK ENSG00000202198 misc_RNA 14.4 1,076,788
4 MALAT1 ENSG00000251562 lncRNA 13.6 786,192
5 ALAS2 ENSG00000158578 protein_coding 13.0 739,891
6 B2M ENSG00000166710 protein_coding 12.9 547,553
7 AL355075.4 ENSG00000259001 lncRNA 12.9 612,534
8 TENT5C ENSG00000183508 protein_coding 12.4 302,729
9 BNIP3L ENSG00000104765 protein_coding 12.3 523,377
10 SLC25A37 ENSG00000147454 protein_coding 12.2 455,526

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.0
bar=donor   line=cohort median 		11.8 11.8 5.1%
2 S100A9 protein_coding 12.1
bar=donor   line=cohort median 		13.1 13.1 2.4%
3 IL1B protein_coding 6.1
bar=donor   line=cohort median 		6.9 6.9 12.0%
4 CXCL8 protein_coding 6.9
bar=donor   line=cohort median 		7.6 7.6 31.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.5
bar=donor   line=cohort median 		4.0 4.0 36.0%
6 FCGR3B protein_coding 10.5
bar=donor   line=cohort median 		11.3 11.3 6.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.7
bar=donor   line=cohort median 		10.9 10.9 34.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.7
bar=donor   line=cohort median 		5.3 5.3 88.0%
9 CD3E protein_coding 4.3
bar=donor   line=cohort median 		2.6 2.6 99.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.6
bar=donor   line=cohort median 		6.3 6.3 72.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.1
bar=donor   line=cohort median 		3.4 3.4 79.1%
12 GNLY protein_coding 4.2
bar=donor   line=cohort median 		4.9 4.9 14.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.9
bar=donor   line=cohort median 		6.6 6.6 34.6%
14 HBA1 protein_coding 3.9
bar=donor   line=cohort median 		2.6 2.6 64.7%
15 HBA2 protein_coding 6.7
bar=donor   line=cohort median 		5.6 5.6 62.7%
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